Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P32071
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P32071-F1 | Predicted | AlphaFoldDB |
No variants for P32071
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P32071 | |||||
No associated diseases with P32071
1 regional properties for P32071
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 100 - 545 | IPR020846 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| xenobiotic transmembrane transporter activity | Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
| response to cycloheximide | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAFIKDSFW | GQIIYRLSGR | KLFRHNDELP | DYVVPEKYLL | DPKEEVLNSS | DKSQSSENKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QTEGDQATIQ | NEPASEHIIV | TWDGDDDPEN | PYNWPFAWKA | IAAMQIGFLT | VSVYMASAIY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TPGVEEIMNQ | FNINSTLATL | PLTMFVIGYG | IGPLFWSPLS | ENSRIGRTPL | YIITLFIFFI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LQIPTALSNH | IAGLSVLRVI | AGFFAAPALS | TGGASYGDFI | AMHYYSIALG | VWSIFAVAGP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SIGPLIGAAV | INRSHDADGW | RWSFWFMAIL | SGVCFIVLSF | SLPETYGKTL | LRRKAERLRK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LTGNNRIISE | GELEDGHKTT | SQVVSSLLWR | PLEITMLEPV | VFLIDIYIAL | VYSIMYLIFE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SVPIVYAGIH | HFTLVEMGAT | YVSTIIGIII | GGAIYLPTVY | YKFTKKLLAG | QNVTPEVFLP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PAIFGAICMP | IGVFIFGWTS | SPDINWFVPL | IGMALFAVGA | FIIFQTLFNY | MAVSFKVEYL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ASVFSSNAFF | RSVSAGAFPL | FGRALYNNLS | IDKFPVGWGS | SILGFISLGM | IAIPVFFYLN |
| 550 | |||||
| GPKLRARSKY | AY |