P32001

PR
Gene name
rpoD
Protein name
RNA polymerase sigma factor RpoD
Names
IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IgG Fc receptor II-c, CDw32, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, CD67 antigen, Carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95, Sigma-70
Species
Buchnera aphidicola subsp Schizaphis graminum (strain Sg)
KEGG Pathway
bas:BUsg_052
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

39-121 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P32001

Entry ID Method Resolution Chain Position Source
AF-P32001-F1 Predicted AlphaFoldDB

No variants for P32001

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P32001

No associated diseases with P32001

12 regional properties for P32001

Type Name Position InterPro Accession
domain RNA polymerase sigma-70 407 - 420 IPR000943-1
domain RNA polymerase sigma-70 431 - 439 IPR000943-2
domain RNA polymerase sigma-70 555 - 567 IPR000943-3
domain RNA polymerase sigma-70 576 - 602 IPR000943-4
domain RNA polymerase sigma factor 70, region 1.1 5 - 78 IPR007127
domain RNA polymerase sigma-70 region 3 462 - 537 IPR007624
domain RNA polymerase sigma-70 region 2 383 - 452 IPR007627
domain RNA polymerase sigma-70 region 4 551 - 604 IPR007630
domain RNA polymerase sigma factor 70, non-essential domain 139 - 352 IPR007631
domain RNA polymerase sigma-70 region 1.2 98 - 128 IPR009042
domain RNA polymerase sigma factor RpoD, C-terminal 379 - 615 IPR012760
domain RNA polymerase sigma-70 like domain 379 - 604 IPR014284

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
sigma factor activity Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.

1 GO annotations of biological process

Name Definition
DNA-templated transcription initiation The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEHNPKSQLK LLVTHGKEQG YLTYAEVNDH LPEEIIDSEQ IDDIIQMIND MGIQVVEEAP
70 80 90 100 110 120
DADDLILNEI NTDTDEDAVE AATQVLSSVE SELGRTTDPV RMYMREMGTV ELLTREGEID
130 140 150 160 170 180
IAKRIEEGIN QVQSSVSEYP EAITYLLEQY DRIKTGQIRL SDIITGFVDP NAEEIFSHST
190 200 210 220 230 240
SAIHIGSEIL DNITNDSNEN EDENEDENED EDENSIDPEL ANEKFRELRK QYTNTSNTIK
250 260 270 280 290 300
NKNRNHQDSL LEIYNLSEIF KQFRLVPKQF DHLVNNMRNM MNRVRKQERK IMKLCIEECK
310 320 330 340 350 360
IPKKIFLKIF SGKETDQNWF KKEQSSNQSW SKKLEEIKEK VFSSMKKLKQ IEKETGLTIE
370 380 390 400 410 420
QVKDINKRMS IGEAKAKRAK KEMVEANLRL VISIAKKYTN RGLQFLDLIQ EGNIGLMKAV
430 440 450 460 470 480
DKFEYRRGYK FSTYATWWIR QAITRSIADQ ARTIRIPVHM IETINKLNRI SRQMLQEIGR
490 500 510 520 530 540
EPTPEELSEK MLIPEDKIRK VLKIAKEPIS METPIGDDDD SHLGDFIEDT TLELPLDSAT
550 560 570 580 590 600
SESLRSATHD VLSGLTAREA KVLRMRFGID MNTDHTLEEV GKQFDVTRER IRQIEAKALR
610
KLRHPSRSEV LRSFLDD