P31813

PR
Gene name
rpo1N
Protein name
DNA-directed RNA polymerase subunit Rpo1N
Names
DNA-directed RNA polymerase subunit A'
Species
Thermococcus celer
KEGG Pathway
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

85-217 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P31813

Entry ID Method Resolution Chain Position Source
AF-P31813-F1 Predicted AlphaFoldDB

No variants for P31813

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P31813

No associated diseases with P31813

6 regional properties for P31813

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 321 - 487 IPR000722
domain RNA polymerase, N-terminal 211 - 515 IPR006592
domain RNA polymerase Rpb1, domain 3 490 - 672 IPR007066
domain RNA polymerase Rpb1, domain 1 6 - 319 IPR007080
domain RNA polymerase Rpb1, domain 5 811 - 876 IPR007081
domain RNA polymerase Rpb1, domain 4 699 - 804 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQSIKKVIGS IDFGILSPQE IRKMSAAEIT VPDTYDEDGY PIEGGLMDKR LGVIDPGLRC
70 80 90 100 110 120
ETCGARAGEC PGHFGHVELA RPVIHVGFAK TIHRVLESTC RECGRIKLTD EEIEEYFHKF
130 140 150 160 170 180
EVTGNRKKAK DRLIKEIHKK AKERMVCPHC GSPQFPIKFE RPTVYWELRK DEEGNEYKHR
190 200 210 220 230 240
MMPSEVRDRL EKIPDRDLPL IGLDAEKARP EWMVLTVLPV PPVTMRPSIT LESGIRAEDD
250 260 270 280 290 300
LTHKLVDIIR INNRLKSNIE AGAPQLIIED LWDLLQYHVT TYINNETSGI PPAKHKSGRP
310 320 330 340 350 360
LKTLSQRLKG KEGRFRGNLS GKRVNFSART VISPDPMISI NEVGVPMAIA MELTVPEKVT
370 380 390 400 410 420
EFNFEKLRKM VLNGPEKYPG ANYVIDPEGR RIRLMENNLE TVAEKLDIGW TVERHLLDGD
430 440 450 460 470 480
VVLFNRQPSL HRMSIMAHRV RVMPYRTFRL NLSVCPPYNA DFDGDEMNLH VPQTEEAQAE
490 500 510 520 530 540
AKILMEVQNH IISPRYGGPL IAGIQDHISG GYLLTREGAY FERTEVEQML MFAGVDVDRL
550 560 570 580 590 600
PEPDKVENGV ELWSGKTIFS LLLPKDLTIW YRNKLCDEPG RCEALEKLIE EKLIPDEEEV
610 620 630 640 650 660
RALAYDGFTY ILNGKLLSGA IDKTAYGRED GKLLDIIVRE YGVERARQFL DQVTKLAIWV
670 680 690 700 710 720
ITHKGFTTAI DDEDLPTEAL DRIREIIREA EERVNRLIEA YRNGELEPIP GKTLEETLES
730 740 750 760 770 780
KIMAALAEAR DNAGKVAERY LGMSNHAVIM AKTGARGKIL NITQMAAMLG QQSIRGKRLY
790 800 810 820 830 840
RGYRERVLTH FKPGDLGARA RGFVINSYKS GLTPQEYFFH AMGGREGLVD TAVRTAQSGY
850 860 870 880 890 900
MQRRLINALQ DLKVEYDGTV RDPTGIIVQF RYGEDGIDPM RSWKGKTIDV NRVVLRTLLK
LRGKG