P31764

PR
Gene name
galT (HI_0820)
Protein name
Galactose-1-phosphate uridylyltransferase
Names
Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_0820
EC number
2.7.7.12: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-133 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P31764

Entry ID Method Resolution Chain Position Source
AF-P31764-F1 Predicted AlphaFoldDB

3 variants for P31764

Variant ID(s) Position Change Description Diseaes Association Provenance
221 I>V strain: RM 7004 [UniProt] No
229 I>V strain: RM 7004 [UniProt] No
334 E>D strain: RM 7004 [UniProt] No

No associated diseases with P31764

16 regional properties for P31764

Type Name Position InterPro Accession
domain Immunodeficiency lentiviral matrix, N-terminal 2 - 131 IPR000071
domain Reverse transcriptase domain 640 - 830 IPR000477
domain Retroviral nucleocapsid Gag protein p24, N-terminal 146 - 270 IPR000721
domain Integrase, C-terminal, retroviral 1376 - 1423 IPR001037
domain Integrase, catalytic core 1206 - 1357 IPR001584
domain Zinc finger, CCHC-type 391 - 408 IPR001878-1
domain Zinc finger, CCHC-type 413 - 429 IPR001878-2
active_site Aspartic peptidase, active site 519 - 530 IPR001969
domain Peptidase A2A, retrovirus, catalytic 517 - 586 IPR001995
domain Ribonuclease H domain 1029 - 1150 IPR002156
domain Integrase, N-terminal zinc-binding domain 1156 - 1198 IPR003308
domain Reverse transcriptase connection 914 - 1014 IPR010659
domain Reverse transcriptase thumb 837 - 898 IPR010661
domain Retropepsins 503 - 594 IPR018061
domain Retropepsin-like catalytic domain 508 - 588 IPR034170
domain Retroviral nucleocapsid Gag protein p24, C-terminal domain 277 - 350 IPR045345

Functions

Description
EC Number 2.7.7.12 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
UDP-glucose:hexose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
galactose catabolic process via UDP-galactose The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTALFEPTEH PHRRYNPLID QWVLVSPHRA KRPWQGQQEK VNEEQKPSYD PTCYLCPSNK
70 80 90 100 110 120
RITGELNPDY RKPYVFKNDF SALLEDTPAP EKSSDPLFQS SQARGESRVI CFSPDHSKTL
130 140 150 160 170 180
PLLTALEIEE VIKVWQEQLR ELGAKYQWVQ IFENKGAAMG CSNPHPHGQI WANSFLPNEV
190 200 210 220 230 240
AREDRTQRDY LLKHGSVMLV DYVKRELALK ERIVVETEHW IALVPYWAIW PFETLLLPKT
250 260 270 280 290 300
HVKRLTELSD EQSKDLAVIL KKLTTKYDNL FETSFPYSMG FHAAPFNGED NEHWQLHAHF
310 320 330 340
YPPLLRSATV RKFMVGYEML GENQRDLTAE QAAERLRALS EVHYKERTK