P31661

PR
Gene name
SLC6A8
Protein name
Sodium- and chloride-dependent creatine transporter 1
Names
CT1, Creatine transporter 1, Solute carrier family 6 member 8
Species
Oryctolagus cuniculus (Rabbit)
KEGG Pathway
ocu:100009280
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P31661

Entry ID Method Resolution Chain Position Source
AF-P31661-F1 Predicted AlphaFoldDB

No variants for P31661

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P31661

No associated diseases with P31661

No regional properties for P31661

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P31661

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Apical cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
creatine:sodium symporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).

2 GO annotations of biological process

Name Definition
creatine transmembrane transport The directed movement of creatine across a membrane.
neurotransmitter transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKKSAENGI YSVSGDEKKG PLIAPGPDGA PAKGDGPAGL GAPGGCLAVP PRETWTRQMD
70 80 90 100 110 120
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS
130 140 150 160 170 180
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD
190 200 210 220 230 240
CVEIFRHEDC ANGSLANLTC DQLAERRSPV IEFWENKVLR LSGGLEVPGA LNSEVTLCLL
250 260 270 280 290 300
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL
310 320 330 340 350 360
RSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF
370 380 390 400 410 420
SILGFMATEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV
430 440 450 460 470 480
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVQMAGMYVF QLFDYYSASG
490 500 510 520 530 540
TTLLWQAFWE CVAVAWVYGA DRFMDDIACM IGYRPCPWMK WCWSFFTPLV CMGIFIFNIV
550 560 570 580 590 600
YYKPLVYNKT YVYPWWGEAM GWAFALSSML CVPLHLLGCL LRAKGTMAER WQHLTQPVWG
610 620 630
LHHLEYRAQD ADVRGLTTLT PVSESSKVVV VESVM