P31549
Gene name |
thiP (yabK, b0067, JW0066) |
Protein name |
Thiamine transport system permease protein ThiP |
Names |
|
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b0067 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P31549
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P31549-F1 | Predicted | AlphaFoldDB |
No variants for P31549
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P31549 | |||||
No associated diseases with P31549
No regional properties for P31549
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P31549 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing | A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| thiamine transmembrane transport | The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATRRQPLIP | GWLIPGVSAT | TLVVAVALAA | FLALWWNAPQ | DDWVAVWQDS | YLWHVVRFSF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WQAFLSALLS | VIPAIFLARA | LYRRRFPGRL | ALLRLCAMTL | ILPVLVAVFG | ILSVYGRQGW |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LATLCQSLGL | EWTFSPYGLQ | GILLAHVFFN | LPMASRLLLQ | ALENIPGEQR | QLAAQLGMRS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WHFFRFVEWP | WLRRQIPPVA | ALIFMLCFAS | FATVLSLGGG | PQATTIELAI | YQALSYDYDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ARAAMLALLQ | MVCCLGLVLL | SQRLSKAIAP | GTTLLQGWRD | PDDRLHSRIC | DTVLIVLALL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLLPPLLAVI | VDGVNRQLPE | VLAQPVLWQA | LWTSLRIALA | AGVLCVVLTM | MLLWSSRELR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ARQKMLAGQV | LEMSGMLILA | MPGIVLATGF | FLLLNNTIGL | PQSADGIVIF | TNALMAIPYA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LKVLENPMRD | ITARYSMLCQ | SLGIEGWSRL | KVVELRALKR | PLAQALAFAC | VLSIGDFGVV |
| 490 | 500 | 510 | 520 | 530 | |
| ALFGNDDFRT | LPFYLYQQIG | SYRSQDGAVT | ALILLLLCFL | LFTVIEKLPG | RNVKTD |