Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P31397
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P31397-F1 | Predicted | AlphaFoldDB |
No variants for P31397
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P31397 | |||||
No associated diseases with P31397
No regional properties for P31397
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P31397 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plasma membrane of cell tip | The portion of the plasma membrane surrounding the cell tip. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mating-type factor pheromone receptor activity | Combining with a mating-type factor pheromone to initiate a change in cell activity. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| G protein-coupled receptor signaling pathway | The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| pheromone response MAPK cascade | A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion. |
| pheromone-dependent signal transduction involved in conjugation with cellular fusion | A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae. |
| positive regulation of meiotic cell cycle | Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLPIGIFYQF | YAYFALVLSI | PILYMQLRAR | NIPCLLLLFW | LTLTTLIYVV | ESAIWSNPYA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ETIRWMGYGL | CDITSRIVTC | SSIGIPASAF | TLVLYLDTVI | RRDHPLKRYE | NWIWHVCLSI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLPLIIMAMM | VPLESNRYVV | ICMNGCYSSF | YQTWYTLLFF | YIPPCLLSFG | GLFFVSRIVV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LYWRRQRELQ | QFFQRDSQLT | SKRFLRLLCL | AAVFFLGYFP | LTIFMVVANG | KLQQFLPFNH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ELVEAWHQES | ITYYPTTKVG | LNDWVPPTVL | YLMSLFFSTS | GGWTEKVALI | LWSLLVWLPF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TKNTALGRHA | QFKLDCCKSI | ESTMAGKTLD | STDFKEKCLV | LERQWSKSSI | PSDNSSELQD |
| AAKYV |