Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P30667
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P30667-F1 | Predicted | AlphaFoldDB |
No variants for P30667
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P30667 | |||||
No associated diseases with P30667
7 regional properties for P30667
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA polymerase sigma factor 54 interaction domain | 205 - 433 | IPR002078 |
| domain | DNA binding HTH domain, Fis-type | 584 - 621 | IPR002197 |
| domain | GAF domain | 28 - 181 | IPR003018 |
| domain | AAA+ ATPase domain | 225 - 376 | IPR003593 |
| binding_site | Sigma-54 interaction domain, ATP-binding site 1 | 229 - 242 | IPR025662 |
| binding_site | Sigma-54 interaction domain, ATP-binding site 2 | 291 - 306 | IPR025943 |
| conserved_site | Sigma-54 interaction domain, conserved site | 417 - 426 | IPR025944 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| metal ion binding | Binding to a metal ion. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| nitrogen fixation | The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide. |
| phosphorelay signal transduction system | A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins. |
| positive regulation of DNA-templated transcription initiation | Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPGAMRQSTS | NLELLTIYEV | SKILGSSLDL | QQTLREVLRA | LAYQLQMHRG | RVYLVGEDNV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LRLVAANGLS | NEAAAQIEFR | DGEGITGRIL | KTGMPAVVPN | LAEEPLFLNR | TGGREDLDEQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VASLVGVPIK | AAGVVVGVLT | IDRISDEGPQ | GHFGSDVRFL | TMVANLIGQT | VRLHRTVAEE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RRFMMRETFR | MQKELRPVAA | PINDVVCTSP | NMLEVMAQVH | RVAPFKSTVL | IRGESGTGKE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LIARAIHNMS | PRKDAPFIRV | NCAALPESLL | ESELFGHEKG | AFTGAQKDHK | GRFELASGGT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LFLDEIGDIS | PNFQAKLLRV | LQEQEFERVG | GSKTIKTDVR | LICATNLNLE | EAVGHGKFRA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DLYFRINVVT | IHLPPLRERR | QDIGPLARHF | VAKFAKDNGM | ALVMEDEALE | VLNRCTWPGN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VRELENCIER | AATQSRDGII | RTESLSCSLN | LCNSSVLFQY | RTLGASVGGL | APSMGPGAIN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RVPPGRPGGP | AAANAPKTPA | MPAPVPEPAG | AAAARGRPAR | RVVPRPLAGL | RRRPAGGSGP |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PDPACPCPSR | APLPPQAPPP | SPAAAPPPAA | EVPLDEPESG | SLRDRLLWAM | ERTGWVQAKA |
| 610 | 620 | ||||
| ARLLGMTTRQ | VSYALRKYNI | EIKRF |