P30601

PR
Gene name
CHS2
Protein name
Chitin synthase 2
Names
Chitin-UDP acetyl-glucosaminyl transferase 2, Class-I chitin synthase 2
Species
Exophiala dermatitidis (Black yeast) (Wangiella dermatitidis)
KEGG Pathway
EC number
2.4.1.16: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-94 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P30601

Entry ID Method Resolution Chain Position Source
AF-P30601-F1 Predicted AlphaFoldDB

No variants for P30601

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P30601

No associated diseases with P30601

1 regional properties for P30601

Type Name Position InterPro Accession
domain Chitin synthase N-terminal 19 - 93 IPR013616

Functions

Description
EC Number 2.4.1.16 Hexosyltransferases
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
chitin synthase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).

3 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
chitin biosynthetic process The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
conidium formation The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAYNRLGSPQ RDGPYSPSAQ PQYDSRSPSP GRPLQPYIHP DEAYARQQPL HLQMPTASDD
70 80 90 100 110 120
RLAMQPTYSV ENVHNPQAYG QQYGQHLPDS GDMGYGRNDY IVSPEEHHDA YYTQPYSPHP
130 140 150 160 170 180
QGDYALDPYP SHDEPYRPDT DNVPILQPDS AYGPDPHTQP GMDYDDYQEE PRPTPSPAPI
190 200 210 220 230 240
RRWKTVKEVQ LFNGNLVLDC PVPPKLLANV PHAKPPERDE FTHMRYSAAT CDPSDFHNER
250 260 270 280 290 300
FTLRQRLFAK PRQTELFIVV TMYNEDEFLF ARTMIGVFKN IEFMCNRSSS KTWGKEAWKK
310 320 330 340 350 360
IVVCIVSDGR AKINPRTRAV LAGLGVYQDG IAKQQVNGKD VTAHIYEYTT QVGLELKGTQ
370 380 390 400 410 420
VSLKPRSATP VQLLFCLKEK NQKKINSHRW FFQAFGRVLD PNICVLIDAG TKPGKDSIYQ
430 440 450 460 470 480
LWKAFDLEPM CGGACGEIKV MLDHGKKLLN PLVATQNFEY KMSNILDKPL ESAFGFISVL
490 500 510 520 530 540
PGAFCAYRYV ALQNDKNGVG PLEKYFKGET MHADAGVFTA NMYLAEDRIL CFELVSKRNC
550 560 570 580 590 600
RWILQYVKSA TGETDVPDRI PEFVLQRRRW LNGSFFAAVY AVAHVYQLWR TDHSFLRKLM
610 620 630 640 650 660
FLIEFTYQTI NMLFAWFAIG NFFLVFRLLT ASLGTKETLG TAGTVLGVVF EFVYLGTLLY
670 680 690 700 710 720
CFILSMGNRP QGNPKSYMMM VIFWSVLMVW LTFASIFLTV KSIETEVQQK DFSFSTIFNN
730 740 750 760 770 780
STFFGLIVSL ASTYVLWFVA SFLFFDPWHM FTCFLQYIVL TPTYINVLNI YAFCNTHDIT
790 800 810 820 830 840
WGTKGDDKAE KLPSANVKPG GKVDVLIPQD DGDLNAQYDS ELKKFATKPP KEVKAPNPAD
850 860 870 880 890 900
KQEDYYKSFR SNVVTAWMIT NFILVAAVLN IAGFDRINVH DTQQQNSTIY LAVILWSVAG
910 920
LSLFRFTGAC WFLVVRMVSL EIWSVCKV