P30309
Gene name |
cdc25-1-b (cdc25b) |
Protein name |
M-phase inducer phosphatase 1-B |
Names |
|
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:398119 |
EC number |
3.1.3.48: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P30309
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P30309-F1 | Predicted | AlphaFoldDB |
No variants for P30309
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P30309 | |||||
No associated diseases with P30309
1 regional properties for P30309
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Rhodanese-like domain | 386 - 508 | IPR001763 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.48 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein tyrosine phosphatase activity | Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| positive regulation of cell cycle G2/M phase transition | Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle. |
| protein dephosphorylation | The process of removing one or more phosphoric residues from a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAESHIMSSE | APPKTNTGLN | FRTNCRMVLN | LLREKDCSVT | FSPEQPLTPV | TDLAVGFSNL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STFSGETPKR | CLDLSNLGDE | TAPLPTESPD | RISSGKVESP | KAQFVQFDGL | FTPDLGWKAK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KCPRGNMNSV | LPRLLCSTPS | FKKTSGGQRS | VSNKENEGEL | FKSPNCKPVA | LLLPQEVVDS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QFSPTPENKV | DISLDEDCEM | NILGSPISAD | PPCLDGAHDD | IKMQNLDGFA | DFFSVDEEEM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ENPPGAVGNL | SSSMAILLSG | PLLNQDIEVS | NVNNISLNRS | RLYRSPSMPE | KLDRPMLKRP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VRPLDSETPV | RVKRRRSTSS | SLQPQEENFQ | PQRRGTSLKK | TLSLCDVDIS | TVLDEDCGHR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QLIGDFTKVY | ALPTVTGRHQ | DLRYITGETL | AALIHGDFSS | LVEKIFIIDC | RYPYEYDGGH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IKGALNLHRQ | EEVTDYFLKQ | PLTPTMAQKR | LIIIFHCEFS | SERGPKMCRF | LREEDRARNE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YPSLYYPELY | LLKGGYKDFF | PEYKELCEPQ | SYCPMHHQDF | REELLKFRTK | CKTSVGDRKR |
| REQIARIMKL |