Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P29741

Entry ID Method Resolution Chain Position Source
AF-P29741-F1 Predicted AlphaFoldDB

No variants for P29741

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P29741

No associated diseases with P29741

3 regional properties for P29741

Type Name Position InterPro Accession
domain ATP-dependent helicase, C-terminal 527 - 684 IPR006555
domain RAD3-like helicase, DEAD 197 - 262 IPR010614
domain Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type 16 - 293 IPR014013

Functions

Description
EC Number 3.6.4.12 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA helicase activity Unwinding of a DNA helix, driven by ATP hydrolysis.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
nucleobase-containing compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLHSQIKSDI KQCYENLGNQ LDNFIPRRAQ NYLVAEIAKT LAGEYHQKHR MLVGEAGTGI
70 80 90 100 110 120
GKSLAYLLGG IPFALFNNKK LLISTATVAL QEQLINKDLP LFNRIYPKEF SFILAKGRQR
130 140 150 160 170 180
YCCNHKLEAC CATNNDQQVT LWEEKPKKSD LDLLRRMLKA TRDGKWDGDR DSWPTTIPDR
190 200 210 220 230 240
VWPQIMADKH SCHAGLPQHR SCPFAKAREH LDKADVIIAN HALLMADIEL GGGVILPEPE
250 260 270 280 290 300
QTIYVIDEAH HLPKVARDFS SAASSLKGAA TWLEKLNQTI GKLAELAEYK KAARFQDAIL
310 320 330 340 350 360
ENIQHLIPTL RQVANNVDVG MFSKDGIYRF EHGELPAWLE QEAKGCKDAS KKALQSLGKI
370 380 390 400 410 420
HDLISERLKD NEIQQRLGEQ ALAESGVYLQ RLENLEKVWA LMAQPKKDKG APLARWIEKN
430 440 450 460 470 480
PDNEGDYIIQ VSPLEVGYRL DQLLWSRAAG AILVSATLRA LNQFTYFCRQ VGIYEMDSTR
490 500 510 520 530 540
FLALASPFDY QNNARLVIPA LSLEPQADKF TDLLIKTLPE YLEGETASLV LFSSYWQMNK
550 560 570 580 590 600
VADELRPLAK KNKWELLVQG EESRHITLKK HKDNCKSGKP SILFGTGSFS EGLDLPGDLL
610 620 630 640 650 660
KNLIITKIPF GVPTSPVEEA HAEYIESCGG NPFMQISVPE ASKKLIQSVG RLIRKEDDMG
670 680 690
RVVLLDRRII NRRYGKALLD SLPPFKRVIE YS