P29361

PR
Gene name
YWHAZ
Protein name
14-3-3 protein zeta/delta
Names
Protein kinase C inhibitor protein 1, KCIP-1
Species
Ovis aries (Sheep)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

36-108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P29361

Entry ID Method Resolution Chain Position Source
AF-P29361-F1 Predicted AlphaFoldDB

No variants for P29361

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P29361

No associated diseases with P29361

3 regional properties for P29361

Type Name Position InterPro Accession
conserved_site 14-3-3 protein, conserved site 41 - 51 IPR023409-1
conserved_site 14-3-3 protein, conserved site 211 - 230 IPR023409-2
domain 14-3-3 domain 3 - 242 IPR023410

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Melanosome
  • Located to stage I to stage IV melanosomes
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
melanosome A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.

2 GO annotations of molecular function

Name Definition
phosphoserine residue binding Binding to a phosphorylated serine residue within a protein.
protein sequestering activity Binding to a protein to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.

3 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.
regulation of ERK1 and ERK2 cascade Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDKNELVQKA KLAEQAERYD DMAACMKSVT EQGAELSNEE RNLLSVAYKN VVGARRSSWR
70 80 90 100 110 120
VVSSIEQKTE GAEKKQQMAR EYREKIETEL RDICNDVLSL LEKFLIPNRS QPESKVFYLK
130 140 150 160 170 180
MKGDYYRYLA EVAAGDDKKG IVDQSQQAYQ EAFEISKKEM QPTHPIRLGL ALNFSVFYYE
190 200 210 220 230 240
ILNSPEKACS LAKTAFDEAI AELDTLSEES YKDSTLIMQL LRDNLTLWTS DTQGDEAEAG
EGGEN