P29158
Gene name |
rpo1C |
Protein name |
DNA-directed RNA polymerase subunit Rpo1C |
Names |
DNA-directed RNA polymerase subunit A'' |
Species |
Thermococcus celer |
KEGG Pathway |
|
EC number |
2.7.7.6: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P29158
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P29158-F1 | Predicted | AlphaFoldDB |
No variants for P29158
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P29158 | |||||
No associated diseases with P29158
1 regional properties for P29158
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA polymerase Rpb1, domain 5 | 50 - 334 | IPR007081 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.6 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| DNA-directed RNA polymerase complex | A protein complex that possesses DNA-directed RNA polymerase activity. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-directed 5'-3' RNA polymerase activity | Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription | The synthesis of an RNA transcript from a DNA template. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVAAKTIKGM | VDKAELPDNI | KEELYAKLIE | YNKKYKLKKA | EVQAIIDETV | KEYQKALIEP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GEAIGTVAAQ | SIGEPSTQMT | LNTFHYAGVA | EINVTLGLPR | IIEIVDARKN | PSTPIMTVYL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEEHRYDREK | ALEVARRIEG | TSLENLARET | TIDILNFEFI | VEIDPERLEK | AGLDMERIQR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KLESSFKSAE | FEVDGYTVIM | RPKKVGKISS | LRRLAEKVKK | HRLKGLSRVG | KTVITKDSKT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GEYIIRTEGS | NFKQVLKVPG | VDPTRTRTND | IREIAEVLGI | EAARNAIIDE | ILKTMEEQGL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EVDVRHIMLV | ADMMTLDGVI | RPIGRHGIVG | EKASVLARAA | FEITTQHLFE | AAERGAVDPL |
| 370 | 380 | 390 | |||
| NGVVENVLIG | QPVPVGTGTV | KLAMNLPLRP | KRE |