P28861

PR
Gene name
fpr
Protein name
Flavodoxin/ferredoxin--NADP reductase
Names
Ferredoxin (flavodoxin):NADP(+) oxidoreductase, Ferredoxin--NADP reductase, FNR, Flavodoxin--NADP reductase, FLDR, Methyl viologen resistance protein A, dA1
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b3924
EC number
1.18.1.2: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

166-248 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P28861

Entry ID Method Resolution Chain Position Source
1FDR X-ray 170 A A 1-248 PDB
2XNJ X-ray 190 A A/B 2-247 PDB
AF-P28861-F1 Predicted AlphaFoldDB

No variants for P28861

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P28861

No associated diseases with P28861

3 regional properties for P28861

Type Name Position InterPro Accession
domain FAST kinase leucine-rich 429 - 499 IPR010622
domain FAST kinase-like protein, subdomain 2 511 - 601 IPR013579
domain RAP domain 695 - 756 IPR013584

Functions

Description
EC Number 1.18.1.2 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
ferredoxin-NADP+ reductase activity Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+.

3 GO annotations of biological process

Name Definition
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
response to superoxide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
response to xenobiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P27787 FDX1 Ferredoxin-1, chloroplastic Zea mays (Maize) PR
10 20 30 40 50 60
MADWVTGKVT KVQNWTDALF SLTVHAPVLP FTAGQFTKLG LEIDGERVQR AYSYVNSPDN
70 80 90 100 110 120
PDLEFYLVTV PDGKLSPRLA ALKPGDEVQV VSEAAGFFVL DEVPHCETLW MLATGTAIGP
130 140 150 160 170 180
YLSILQLGKD LDRFKNLVLV HAARYAADLS YLPLMQELEK RYEGKLRIQT VVSRETAAGS
190 200 210 220 230 240
LTGRIPALIE SGELESTIGL PMNKETSHVM LCGNPQMVRD TQQLLKETRQ MTKHLRRRPG
HMTAEHYW