P28788

PR
Gene name
ntrB
Protein name
Sensory histidine kinase/phosphatase NtrB
Names
Nitrogen regulation protein NR(II), Nitrogen regulator II, NRII
Species
Proteus hauseri
KEGG Pathway
EC number
2.7.13.3: Protein-histidine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

81-152 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P28788

Entry ID Method Resolution Chain Position Source
AF-P28788-F1 Predicted AlphaFoldDB

No variants for P28788

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P28788

No associated diseases with P28788

7 regional properties for P28788

Type Name Position InterPro Accession
domain PAS domain 7 - 103 IPR000014
domain Histidine kinase/HSP90-like ATPase 233 - 348 IPR003594
domain Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 129 - 194 IPR003661
domain Signal transduction histidine kinase-related protein, C-terminal 281 - 295 IPR004358-1
domain Signal transduction histidine kinase-related protein, C-terminal 310 - 328 IPR004358-2
domain Signal transduction histidine kinase-related protein, C-terminal 333 - 346 IPR004358-3
domain Histidine kinase domain 136 - 348 IPR005467

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
phosphorelay sensor kinase activity Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.

2 GO annotations of biological process

Name Definition
nitrogen fixation The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.
protein autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
METGNLPDNT LILDSLIHSV LVINQEFIIC YANHAALQVL AQSRRKLFET PFTDLFSYHS
70 80 90 100 110 120
FDAELMQETL ANGQSFTDNE VILVIHNQSH TMSLSAQPIS EQHILLELAP MDSQRRLSQE
130 140 150 160 170 180
QIQQAQQIAA RELVRGLAHE IKNPLGGLRG AAQLLAKSLP DPALTEYTQV IIEQADRLRT
190 200 210 220 230 240
LVDRLLGPQH PGKKTHQSIH HVVERVAQLI SLECPENVTL LKDYDPSLPE LSHYPDQIEQ
250 260 270 280 290 300
VLLNITRNAL QAVEKTGGTI ILRTRTAFQI TLHGERHRLV ARIDVIDTGS GIPPHLQDTL
310 320 330 340
FYPMVSGRED GNGLGLSIAR NLVDQHAGKI EFTSWPGNTE FSIYLPIK