P28582
Gene name |
|
Protein name |
Calcium-dependent protein kinase |
Names |
CDPK |
Species |
Daucus carota (Wild carrot) |
KEGG Pathway |
|
EC number |
2.7.11.1: Protein-serine/threonine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
225-247 (Activation loop from InterPro)
Target domain |
81-339 (Protein kinase domain) |
Relief mechanism |
|
Assay |
|
Autoinhibited structure
Activated structure
1 structures for P28582
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P28582-F1 | Predicted | AlphaFoldDB |
No variants for P28582
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P28582 | |||||
No associated diseases with P28582
7 regional properties for P28582
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Protein kinase domain | 81 - 339 | IPR000719 |
| domain | EF-hand domain | 382 - 453 | IPR002048-1 |
| domain | EF-hand domain | 456 - 522 | IPR002048-2 |
| active_site | Serine/threonine-protein kinase, active site | 201 - 213 | IPR008271 |
| binding_site | Protein kinase, ATP binding site | 87 - 114 | IPR017441 |
| binding_site | EF-Hand 1, calcium-binding site | 395 - 407 | IPR018247-1 |
| binding_site | EF-Hand 1, calcium-binding site | 500 - 512 | IPR018247-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.11.1 | Protein-serine/threonine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| calcium ion binding | Binding to a calcium ion (Ca2+). |
| protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGGCFSKKEY | QADGNGYRSA | PTAYHTVTDQ | SYEKSSQRSQ | PQAQPQPQVQ | QTGPSLKPRQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VHRPESNTIL | GKPFEDIRGK | YTLGKELGRG | QFGCVYQCTE | NSSGQLYACK | SILKRKLVSK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NDKEDIKREI | QILQHLSGQP | NIVEFKGVFE | DRQSVHLVME | LCAGGELFDR | IIAQGHYSER |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AAATICRQIV | NVVHVCHFMG | VMHRDLKPEN | FLLSSKDKDA | MLKATDFGLS | VFIEEGKVYR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NIVGSAYYVA | PEVLRRSYGK | EIDIWSAGVI | LYILLSGVPP | FWAENEKGIF | DAILEGVIDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ESEPWPSVSN | SAKDLVRKML | TQDPRRRITS | AQVLDHPWMR | EGGEASDKPI | DSAVLSRMKQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FRAMNKLKQL | ALKVIAESLS | EEEIKGLKSM | FANMDTDKSG | TITYEELKSG | LARLGSKLSE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VEVQQLMDAA | DVDGNGTIDY | LEFITATMHR | HKLESYEHQA | FQYFDKDNSG | FITKDELESA |
| 490 | 500 | 510 | 520 | 530 | |
| MKEYGMGDEA | TIKDIISEVD | SDNDGRINYD | EFCAMMRRAR | NRRKLFSVSL | TS |