P28268

PR
Gene name
Protein name
Tubulin alpha chain
Names
Species
Euplotes vannus (Marine ciliate) (Moneuplotes vannus)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

392-450 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P28268

Entry ID Method Resolution Chain Position Source
AF-P28268-F1 Predicted AlphaFoldDB

No variants for P28268

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P28268

No associated diseases with P28268

3 regional properties for P28268

Type Name Position InterPro Accession
domain Tubulin/FtsZ, GTPase domain 3 - 246 IPR003008
conserved_site Tubulin, conserved site 142 - 148 IPR017975
domain Tubulin/FtsZ, 2-layer sandwich domain 248 - 392 IPR018316

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
microtubule Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
structural constituent of cytoskeleton The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.

1 GO annotations of biological process

Name Definition
microtubule-based process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MREVISVHIG QGGIQVGNAC WELFCLEHGI QPDGQMPSDK TIGGGDDAFN TFFSETGAGK
70 80 90 100 110 120
HVPRAVLVDL EPTVCDEIRT GTYRQLFHPE QIISGKEDAA NNFARGHYTI GKEIVDLVLD
130 140 150 160 170 180
RIRKLADNCT GLQGFIGFHS VGGGTGSGLG SLLLERLSVD YGKKSKLCFT VYPSPQVSTA
190 200 210 220 230 240
VVEPYNSVLS THSLLEHTDV AVMLDNEAVY DICRRNLDIE RPTYTNLNRL IAQVISSLTA
250 260 270 280 290 300
SLRFDGALNV DITEFQTNLV PYPRIHFMLS SYGPVISAEK AYHEQLSVAE ITNSSFEPAS
310 320 330 340 350 360
MMAKCDPRHG KYMACCMMFR GDVVPKDVNA AVATIKTKRT IQFVDWSPGF KVGINYQPPT
370 380 390 400 410 420
VVPGGDLAKV MRAVCMISNS TAIAEVFSRI DHKFDLMYAK RAFVHWYVGE GMEEGEFSEA
430 440
REDLAALEKD YEEVGIETAE GEGEEEDMAQ