Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P28024
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P28024-F1 | Predicted | AlphaFoldDB |
No variants for P28024
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P28024 | |||||
No associated diseases with P28024
1 regional properties for P28024
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Proteasome beta-type subunit, conserved site | 35 - 82 | IPR016050 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| proteasome core complex | A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex. |
| proteasome core complex, beta-subunit complex | The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis involved in protein catabolic process | The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| ESVARGTAPG | ELHCFPGAGP | VRHTLNPMVT | GTSVLGVKFD | GGVIIAADML | GSYGSLARFR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NISRIMKVNE | NTILGASGDY | ADYQYLKQVI | DQMVIDEELV | GDGHNYSPKA | IHSWLTRVMY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NRRSKMNPLW | NTVVIGGFYN | GESFLGYVDK | LGVAYEAPTI | ATGFGAYLAQ | PLLREVTENK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ATLSKEEARQ | LVDRCMKVLY | YRDARSYNRF | EITTVTESGV | EVEGPLSSET | NWEIAHLISG |
| FE |