Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

219-244 (Activation loop from InterPro)

Target domain

83-343 (Protein kinase domain)

Relief mechanism

Assay

Autoinhibited structure

Activated structure

0 structures for P27966

Entry ID Method Resolution Chain Position Source

No variants for P27966

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P27966

No associated diseases with P27966

3 regional properties for P27966

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 24 - 266 IPR003439
domain AAA+ ATPase domain 48 - 242 IPR003593
conserved_site ABC transporter-like, conserved site 168 - 182 IPR017871

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEAVIKDLIR DQGVRGEGGS TAGLSATPPA SLPGSLTNVK ALQKSPGPQR ERKSSSSSED
70 80 90 100 110 120
RNRMKTLGRR DSSDDWEIPD GQITVGQRIG SGSFGTVYKG KWHGDVAVKM LNVTAPTPQQ
130 140 150 160 170 180
LQAFKNEVGV LRKTRHVNIL LFMGYSTKPQ LAIVTQWCEG SSLYHHLHII ETKFEMIKLI
190 200 210 220 230 240
DIARQTAQGM DYLHAKSIIH RDLKSNNIFL HEDLTVKIGD FGLATVKSRW SGSHQFEQLS
250 260 270 280 290 300
GSILWMAPEV IRMQDKNPYS FQSDVYAFGI VLYELMTGQL PYSNINNRDQ IIFMVGRGYL
310 320 330 340 350 360
SPDLSKVRSN CPKAMKRLMA ECLKKKRDER PLFPQILASI ELLARSLPKI HRSASEPSLN
370 380 390 400 410 420
RAGFQTEDFS LYACASPKTP IQAGGIGEWA VHLLKGLLLG LVVILLLVVC LPCLLQCVSS
430 440
SIRKMIDNSL GYREEYKKLQ EAYKQPERRA