P27752

PR
Gene name
ORF1a
Protein name
Replication protein 1a
Names
Species
Cowpea chlorotic mottle virus (CCMV)
KEGG Pathway
vg:962153
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-44 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P27752

Entry ID Method Resolution Chain Position Source

No variants for P27752

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P27752

No associated diseases with P27752

3 regional properties for P27752

Type Name Position InterPro Accession
domain Alphavirus-like methyltransferase (MT) domain 49 - 398 IPR002588
domain Cucumber mosaic virus 1a protein C-terminal 587 - 665 IPR022184
domain (+) RNA virus helicase core domain 652 - 958 IPR027351

Functions

Description
EC Number
Subcellular Localization
  • Host endoplasmic reticulum membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell endoplasmic reticulum membrane The lipid bilayer surrounding the host cell endoplasmic reticulum.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
mRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASSLDLLKL ISERGADSRG ASDIVEQQAV KQLLEQVDYS KRSKKINIRN KLTPDEENAF
70 80 90 100 110 120
RARYGGAFDL NLTQQYNAPH SLAGALRIAE HYDCLSSFPP LDPIIDFGGS WWHHYSRKDT
130 140 150 160 170 180
RIHSCCPVLG VRDAARHEER LCRMRKLLQE CDDREDLPDF CIDRAESCSV QADWAICIHG
190 200 210 220 230 240
GYDMGYTGLC EAMHSHGVRI LRGTIMFDGA MLFDNEGVLP LLKCRWMKSG KGKSEVIKFD
250 260 270 280 290 300
FMNESTLSYI HSWTNLGSFL TESVHVIGGT TYLLERELLK CNIMTYKIVA TNLKCPKETL
310 320 330 340 350 360
RHCVWFENIS QYVAVNIPED WNLTHWKPVR VAKTTVREVE EIAFRCFKEN KEWTENMKAI
370 380 390 400 410 420
ASILSAKSST VIINGQAIMA GERLNIDEYH LVAFALTMNL YQKYENIRNF YSEMEWKGWV
430 440 450 460 470 480
NHFKTRFWWG GSTATSSTGK IREFLAGKFP WLRLDSYKDS FVFLSKISDV KEFENDSVPI
490 500 510 520 530 540
SRLRSFFSSE DLMERIELEL ESAQKRRREK KKKEVEKIDE EEFQDAIDIP NDAVRDDAKP
550 560 570 580 590 600
EKEPKPEVTV GAEPTGPEEA SRHFAIKEFS DYCRRLDCNA VSNLRRLWAI AGCDGRTARN
610 620 630 640 650 660
KSILETYHRV DDMINLHYPG GQWLYPKKYD YEVGFNDSGL GPKFDDELYV VDKSCICANY
670 680 690 700 710 720
QVLSKNTDSL KAPSCKISLC DGVAGCGKTT AIKSASNIAE HLVVTANKKS AEDVREALFP
730 740 750 760 770 780
HNPSSEIAFK VIRTADSALM HGLPRCKRLL VDEAGLLHYG QLLAVAALCK CQSVLAFGDT
790 800 810 820 830 840
EQISFKSRDA TFRLKYGDLQ FDSRDIVTET WRCPQDVISA VQTLKRGGNR TSKYLGWKSH
850 860 870 880 890 900
SKVSRSISHK EIASPLQVTL SREKFYLTMT QADKAALVSR AKDFPELDKA WIEKHIKTVH
910 920 930 940 950
EAQGVSVDHA VLVRLKSTKC DLFKTEEYCL VALTRHKITF EYLYVGMLSG DLIFRSIS