P27153

PR
Gene name
P2
Protein name
RNA-directed RNA polymerase catalytic subunit
Names
RNA-directed RNA polymerase subunit P2
Species
Dhori virus (strain Indian/1313/61) (Dho)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-174 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P27153

Entry ID Method Resolution Chain Position Source

No variants for P27153

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P27153

No associated diseases with P27153

1 regional properties for P27153

Type Name Position InterPro Accession
domain RNA-directed RNA polymerase, negative-strand RNA virus 286 - 465 IPR007099

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.

1 GO annotations of biological process

Name Definition
viral RNA genome replication The replication of a viral RNA genome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNLFSPRTGL SPTETQELLY AYTGPAPVAY GTRTRAVLEN VLRPYKYFYK EENVPQALHI
70 80 90 100 110 120
KTGQKGPEEI STTSPSSGFH RDSVILLSRE LKAKYPEAFE RLKAWIDCEL LEMEYAELSK
130 140 150 160 170 180
GRQTLSFLRN RNQPAPIALE ETIEYLQQNL GRPIGQSMLS YLRAVMEVLA MPKTTFTYEV
190 200 210 220 230 240
ATNLARFDFE EYDDGETGPL MMHFEKEKKK ITITITQAEL WEKTCTLGTM WKHLERGRLN
250 260 270 280 290 300
RRTIATPSML ARGFVKIVED AARVLLECLP SSGVPVGGEE KLAKLSSKLE AVSEVTGELS
310 320 330 340 350 360
GDQEKFNECL DPDAMRLMWT VFLEDYPQWV KELFNIPFLI FKAKIADIGE GLTYQKEGVV
370 380 390 400 410 420
RVFPFGEMPS EFDELLPNAI KDKEGKIVGI RCTLGMFMGM FNLSSTLLAL IAADRSEITG
430 440 450 460 470 480
DHVESSDDFI HFFKAKSYDD MFKQAELLRW SLKLVGINMS PSKCILISPA GIGEFNSKYH
490 500 510 520 530 540
HRDFVGNVAT DLPSLVPGGK NPSSDLAMGL NVIRHSINTN QMNFISGDLA LRIFTKAYRH
550 560 570 580 590 600
SYMAEGITRR TKFLEAFKKD PVLLNQGAPT VHSVSTLHLD EVCLRYQMHL LGEEELRRIM
610 620 630 640 650 660
NPSNPITART EEVVSFRPEG KLPMILEDNS VGSCFKYTFT RNRTVTDKPH RVLLEKEQQY
670 680 690 700 710
QKITSFVEEC FPELTIGNTT MPGTVKQACK RRLEYIIEQS DLPTEQKRAL LEEMDS