P26745

PR
Gene name
2
Protein name
Terminase, large subunit
Names
DNA-packaging protein gp2
Species
Salmonella phage P22 (Bacteriophage P22)
KEGG Pathway
vg:2944239
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P26745

Entry ID Method Resolution Chain Position Source
4DKW X-ray 202 A A/B/C/D 289-499 PDB
6VI1 X-ray 240 A M/N/O/P/Q/R 1-33 PDB
6XMI X-ray 151 A C/F 1-33 PDB

No variants for P26745

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P26745

No associated diseases with P26745

1 regional properties for P26745

Type Name Position InterPro Accession
domain Terminase, large subunit gp17-like, C-terminal 319 - 470 IPR035421

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
viral terminase complex A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.
viral terminase, large subunit The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
viral DNA genome packaging The packing of viral DNA into a capsid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELDAILDNL SDEEQIELLE LLEEEENYRN THLLYEFAPY SKQREFIDAG HDYPERCFMA
70 80 90 100 110 120
GNQLGKSFTG AAEVAFHLTG RYPGTKGYPA DGKYGGEWKG KRFYEPVVFW IGGETNETVT
130 140 150 160 170 180
KTTQRILCGR IEENDEPGYG SIPKEDIISW KKSPFFPNLV DHLLVKHHTA DGVEDGISIC
190 200 210 220 230 240
YFKPYSQGRA RWQGDTIHGV WFDEEPPYSI YGEGLTRTNK YGQFSILTFT PLMGMSDVVT
250 260 270 280 290 300
KFLKNPSKSQ KVVNMTIYDA EHYTDEQKEQ IIASYPEHER EARARGIPTM GSGRIFQIPE
310 320 330 340 350 360
ETIKCQPFEC PDHFYVIDAQ DFGWNHPQAH IQLWWDKDAD VFYLARVWKK SENTAVQAWG
370 380 390 400 410 420
AVKSWANKIP VAWPHDGHQH EKGGGEQLKT QYADAGFSML PDHATFPDGG NSVESGISEL
430 440 450 460 470 480
RDLMLEGRFK VFNTCEPFFE EFRLYHRDEN GKIVKTNDDV LDATRYGYMM RRFARMMRDI
490
RKPKEKKIPA PIRPVRRGR