Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P26586
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P26586-F1 | Predicted | AlphaFoldDB |
No variants for P26586
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P26586 | |||||
No associated diseases with P26586
3 regional properties for P26586
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | 14-3-3 protein, conserved site | 32 - 42 | IPR023409-1 |
| conserved_site | 14-3-3 protein, conserved site | 202 - 221 | IPR023409-2 |
| domain | 14-3-3 domain | 1 - 233 | IPR023410 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATELKKGPL | PTDIEETVIT | IMREEGVRYI | TAKILRMRLE | SKYQMEFGPH | KAAIDDIVAR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AMQRPEFKKQ | LELALKEKDA | SKSSGGKGSK | RARSAGAEAP | SKTKKEMTEK | PKKPADYPKP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AVSSYLLFVA | DQREELKAKN | PGMQNTAILQ | TLGKMWSDAS | DDVKEHYRKK | AEEDKARFRR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EVDEYKRQGG | KEYGRGGKIK | KDSNAPKRAM | TSFMFFSSDF | RSKHSDLSIV | EMSKAAGAAW |
| 250 | 260 | 270 | |||
| KELGPEERKV | YEEMAEKDKE | RYKREMAALP | K |