P26257
Gene name |
lacZ |
Protein name |
Beta-galactosidase |
Names |
Beta-gal, Lactase |
Species |
Thermoanaerobacterium thermosulfurigenes (Clostridium thermosulfurogenes) |
KEGG Pathway |
|
EC number |
3.2.1.23: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P26257
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P26257-F1 | Predicted | AlphaFoldDB |
No variants for P26257
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P26257 | |||||
No associated diseases with P26257
6 regional properties for P26257
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich | 159 - 267 | IPR006102 |
| domain | Glycoside hydrolase family 2, catalytic domain | 274 - 543 | IPR006103 |
| domain | Glycosyl hydrolases family 2, sugar binding domain | 47 - 153 | IPR006104 |
| conserved_site | Glycoside hydrolase, family 2, conserved site | 320 - 345 | IPR023230 |
| active_site | Glycoside hydrolase, family 2, active site | 374 - 389 | IPR023232 |
| domain | Glycoside hydrolase family 2, domain 5 | 657 - 708 | IPR040605 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.23 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-galactosidase activity | Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate catabolic process | The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRKIIPINNN | WYFKADYEEG | YEKVDDLRSF | ENVNLPHTNI | ELPYNYFDEK | MYQIKSCYKY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PLHISEKYRD | KVIYIHFEGV | MAYAQVYLNG | LYIGEHKGGY | TPFDIRIDEV | YDWKKELNML |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TVVVDSTERS | DIPPKGGQID | YLTYGGIYRE | VSLGIYDDVF | IKNIKVETHG | IYDNEKSLNL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IVHLENLNHQ | SGNVKFKVKI | NDKNGKEVFY | KEFNTYLDAV | KDVYSFNIEN | LKDIKLWDVD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NPNLYEIKVG | MKINNFSDEY | DNKFGFREAV | FKPDGFYLNG | RKLKLRGLNR | HQSYPYVGYA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MPRRVQEKDA | EILKNELHLN | IVRTSHYPQS | KHFLNKCDEL | GLLVFEEIPG | WQYIGNSEWK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KVAEQNLREM | ITRDWNHPSI | ILWGVRINES | QDDDAFYKNM | NKIAHEIDPT | RQTGGVRYIT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NSSFLEDVYT | FNDFIHDGIN | KPLRKQQEVT | GLEHNVPYLV | TEYNGHMYPT | KRFDNEERQM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EHCLRHLRIQ | NASYLDDSIS | GAIGWCAFDY | NTHKDFGSGD | RICYHGVMDM | FRLPKFASYV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| YKSQVSPDIE | PILEPVTFWA | RGERSIGGVI | PLIIFTNCDY | IELQYGNKTK | IDNIYPNRDA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| YKGIPYPPII | IDYDIVKPEM | IGAWGMVWED | LTLKGFYKGN | KVIERKFSRE | PIPTYLYVVP |
| 670 | 680 | 690 | 700 | 710 | |
| DDTILSATQK | DATRIVVKIL | DQYGNLLPFI | NEVIKIEIEG | PAKLQGPNEV | ALIGGA |