Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P26146
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P26146
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P26146 | |||||
No associated diseases with P26146
No regional properties for P26146
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P26146 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| host cell mitochondrion | A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
| host cell nucleus | A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
| virion component | Any constituent part of a virion, a complete fully infectious extracellular virus particle. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| 7-methylguanosine mRNA capping | Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript. |
| cap snatching | A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs. |
| suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host mRNA transcription by directly inhibiting RNA polymerase II activity. |
| suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity | Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses. |
| viral RNA genome replication | The replication of a viral RNA genome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| RITEMIPERN | EQGQTLWSKM | NDAGSDRVMV | SPLAVTWWNR | NGPITNTVHY | PKIYKTYFER |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VERLKHGTFG | PVHFRNQVKI | RRRVDINPGH | ADLSAKEAQD | VIMEVVFPNE | VGARILTSES |
| QLTITK |