P25980

PR
Gene name
ubtf-b (ubf2)
Protein name
Nucleolar transcription factor 1-B
Names
Upstream-binding factor 1-B, UBF-1-B, xUBF-2
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:379116
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-701 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P25980

Entry ID Method Resolution Chain Position Source
AF-P25980-F1 Predicted AlphaFoldDB

No variants for P25980

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P25980

No associated diseases with P25980

6 regional properties for P25980

Type Name Position InterPro Accession
domain High mobility group box domain 111 - 181 IPR009071-1
domain High mobility group box domain 195 - 265 IPR009071-2
domain High mobility group box domain 297 - 363 IPR009071-3
domain High mobility group box domain 421 - 490 IPR009071-4
domain High mobility group box domain 507 - 575 IPR009071-5
domain High mobility group box domain 5 419 - 503 IPR029215

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
positive regulation of transcription by RNA polymerase I Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNGAAGGDTQ GKMTAPKDQD QWSQEDMLTL LQTMKTLLPG QDNSKFKTTE SHLDWNKLAF
70 80 90 100 110 120
KHYSGSMCRQ KWMEISNEVR KFRTLTELIL DADEHVRHPY KGKKLKKHPE FPKKPLTPYF
130 140 150 160 170 180
RFFMEKRAKY AKLHPEMSNL DLTKILSKKY KELPEKKKMK YIQDFQREKQ DFERNMAKFR
190 200 210 220 230 240
EEHPDLMQNP KKSDVPEKPK TPQQLWYNHE RKVYLKLHAD ASTKDIKDAL GKQWSQLPDK
250 260 270 280 290 300
KRLKWIHKAL EQRKQYEGVM REYMQKHPEL NITEEGITRS TLTKAERQLK DKFDGRPTKP
310 320 330 340 350 360
PPNSYSMYCA ELMANMKDVP STERMVLCSQ RWKLLSQKEK DAYHKKCEQR KKDYEVELMR
370 380 390 400 410 420
FLENLPEEEQ QRVLAEEKMV GMKRKRTNTP ASKMATEDAA KVKSRSGQAD KKKAAEERAK
430 440 450 460 470 480
LPETPKTAEE IWQQSVIGDY LARFKNDRAK ALKVMEATWL NMEKKEKIMW IKKAAEDQKR
490 500 510 520 530 540
YERELSDMRS TPAPTTAGKK VKFLGEPKKA PMNGYQKFSQ ELLSNGELNH LPLKERMVEI
550 560 570 580 590 600
GSRWHRISPT QKDYYKKLAE DQQRLYRTQF DTWMKGLSTQ DRAAYKEQNT NKRKSTTKIQ
610 620 630 640 650 660
APSSKSKLVI QSKSDDDEDD EDDEDEEDDD DDDDEDKEDS SEDGDSSDSS SDEDSEEGEE
670 680 690 700
NEDEEDEEDD DEDNEEDDDD NESGSSSSSS SSADSSDSDS N