P25945

PR
Gene name
tonB (STM1737)
Protein name
Protein TonB
Names
Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG Pathway
stm:STM1737
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

35-171 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P25945

Entry ID Method Resolution Chain Position Source
8RD6 NMR - A 154-242 PDB
AF-P25945-F1 Predicted AlphaFoldDB

No variants for P25945

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P25945

No associated diseases with P25945

2 regional properties for P25945

Type Name Position InterPro Accession
domain TonB/TolA, C-terminal 164 - 235 IPR006260
domain TonB, C-terminal 163 - 233 IPR037682

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane; Single-pass membrane protein; Periplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
plasma membrane protein complex Any protein complex that is part of the plasma membrane.

2 GO annotations of molecular function

Name Definition
energy transducer activity The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.
siderophore transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).

2 GO annotations of biological process

Name Definition
bacteriocin transport The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTLDLPRRFP WPTLLSVGIH GAVVAGLLYT SVHQVIELPA PAQPITVTMV SPADLEPPQA
70 80 90 100 110 120
VQPPPEPVVE PEPEPEPEPI PEPPKEAPVV IEKPKPKPKP KPKPKPVKKV EEQPKREVKP
130 140 150 160 170 180
AAPRPASPFE NSAPVRPTSS TASATSKPAV SVPTGPRALS RNQPQYPARA QALRIEGRVK
190 200 210 220 230 240
VKFDVTSAGR VENVQILSAQ PANMFEREVK NAMRKWRYEA GKPGSGLVVN IIFRLNGTAQ
IE