P25659
Gene name |
FUB1 |
Protein name |
Silencing boundary-establishment protein FUB1 |
Names |
Function of boundary protein 1, Proteasome inhibitor PI31-like protein FUB1 |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YCR076C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P25659
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7TEO | EM | 297 A | a/b | 1-250 | PDB |
| AF-P25659-F1 | Predicted | AlphaFoldDB |
12 variants for P25659
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s03-249991 | 18 | G>C | No | SGRP | |
| s03-249978 | 22 | V>A | No | SGRP | |
| s03-249955 | 30 | T>A | No | SGRP | |
| s03-249945 | 33 | C>F | No | SGRP | |
| s03-249930 | 38 | R>H | No | SGRP | |
| s03-249925 | 40 | K>E | No | SGRP | |
| s03-249895 | 50 | S>P | No | SGRP | |
| s03-249730 | 105 | V>L | No | SGRP | |
| s03-249714 | 110 | K>R | No | SGRP | |
| s03-249538 | 169 | G>R | No | SGRP | |
| s03-249496 | 183 | G>R | No | SGRP | |
| s03-249307 | 246 | G>R | No | SGRP |
No associated diseases with P25659
No regional properties for P25659
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P25659 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| proteasome binding | Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIENKVELVA | ELVLESIGKT | EVVSRHTEGT | KSCQVSFRIK | DSPSEKGSTS | FLSELVVIQT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LDDNDKYTVV | IRHGTSITMA | CVVGYSDFKL | PTELKWPLER | ESLPVEPDLK | PIMTQLKRQT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AGSADMPKFD | DEYQAQARQN | QGTAPLNPYP | GLTVTEPSFA | NPAGGYADGD | LYPVGTSHPD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WSGGLPNPLG | NPSSQGGMIF | DPNRRPAPRR | EDMPPGWMPG | SKYDEPFGPG | SGGFGGSGSG |
| GFGGSGSGFI |