P25568

PR
Gene name
ATG22 (AUT4, YCL038C, YCL38C)
Protein name
Autophagy-related protein 22
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YCL038C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

248-319 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P25568

Entry ID Method Resolution Chain Position Source
AF-P25568-F1 Predicted AlphaFoldDB

6 variants for P25568

Variant ID(s) Position Change Description Diseaes Association Provenance
s03-56291 79 K>N No SGRP
s03-56229 100 V>A No SGRP
s03-55969 187 L>V No SGRP
s03-55727 267 I>M No SGRP
s03-55716 271 V>A No SGRP
s03-55672 286 E>Q No SGRP

No associated diseases with P25568

No regional properties for P25568

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P25568

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
  • Vacuole and punctate structures
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of fungal-type vacuolar membrane The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
amino acid transmembrane export from vacuole The directed movement of amino acids out of the vacuole, across the vacuolar membrane.
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSYGTINDMN ESVTNYRIKK AQNNIKGWYA YSFSSEPFVV SAVSTYIPLL LQQFASINGV
70 80 90 100 110 120
KVHDHSIPCL SETGSDSDKC VLGLFNNRIF VDTSSFALYV FSLSVLFQTI IVISVSGIVD
130 140 150 160 170 180
LWGSVKFKGR ILVWFGIVGA LSTVAISKLN DTQIYSLAGL YIVANGCFGV INVVGNSLLP
190 200 210 220 230 240
IFVKDSLKCQ SQGAYEPDKV DSLTTVISGR GASLGYSSAL IVQIVSMFLV ASKKGSKQDV
250 260 270 280 290 300
QVAVLFVGIW WFVWQLPMIW LIDDVTIPIR VDDSTLASAR SPYPGEQDAL GQLNWKNYLS
310 320 330 340 350 360
YGWVSLFESF KHARLLKDVM IFLIAWFIIS DSITTINSTA VLFSKAELHM STLNLIMISV
370 380 390 400 410 420
LTVVNAMLGA FMIPQFLATK FRWTSSQTLM YIIIWASFIP FYGILGFFFN AFGLKHKFEM
430 440 450 460 470 480
FLLAIWYGLS LGGLSAVSRS VFSLIVPPGK ESTFFSMFSI TDKGSSILGP FLVGLLTDKT
490 500 510 520
HNIRYSFYFF FLLLMLSLPV LNCLDVKRGR REAEELSQVL PESERRLD