P25457

PR
Gene name
rpl702 (rpl7b, SPAC3H5.07)
Protein name
60S ribosomal protein L7-B
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC3H5.07
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-116 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

13 structures for P25457

Entry ID Method Resolution Chain Position Source
8ESQ EM 280 A F 1-250 PDB
8ESR EM 320 A F 1-250 PDB
8ETC EM 310 A F 1-250 PDB
8ETG EM 340 A F 1-250 PDB
8ETH EM 380 A F 1-250 PDB
8ETI EM 370 A F 1-250 PDB
8ETJ EM 320 A F 1-250 PDB
8EUG EM 280 A F 1-250 PDB
8EUI EM 310 A F 1-250 PDB
8EUP EM 310 A F 1-250 PDB
8EUY EM 300 A F 1-250 PDB
8EV3 EM 300 A F 1-250 PDB
AF-P25457-F1 Predicted AlphaFoldDB

3 variants for P25457

Variant ID(s) Position Change Description Diseaes Association Provenance
I_3430315_G_T 52 A>D No Jeffares_SNPs
I_3430106_T_C 122 I>V No Jeffares_SNPs
I_3429767_C_T 235 A>T No Jeffares_SNPs

No associated diseases with P25457

4 regional properties for P25457

Type Name Position InterPro Accession
domain Ribosomal protein L30, N-terminal 16 - 85 IPR012988
domain Ribosomal protein L30, ferredoxin-like fold domain 91 - 141 IPR016082
conserved_site Ribosomal protein L30, conserved site 109 - 141 IPR018038
domain Ribosomal protein L7, eukaryotic/archaeal 90 - 250 IPR035808

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVASSTVPSV ASIFAPESLL KKTKAQKQSR EQIVAAAAEK KSARQKKREL IAKRAEAYEA
70 80 90 100 110 120
EYRAAEREQI ELARKARAEG NYFVPHEPKL IFVVRIRGIN NIPPKARKIM QLLRLLQINN
130 140 150 160 170 180
GIFVKFNKAI KEMLQVVEPY VTYGIPNHKT VRELIYKRGF GKVNKQRIPL SDNAIIEAAL
190 200 210 220 230 240
GKYSILSVED LIHEIYTVGP NFKQAANFLW PFKLSSPLGG WRERKFKHFI EGGDAGKRDE
HINGLVQKML