P25351
Gene name |
YCR023C (YCR23C, YCR241) |
Protein name |
Uncharacterized membrane protein YCR023C |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YCR023C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P25351
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P25351-F1 | Predicted | AlphaFoldDB |
13 variants for P25351
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s03-160041 | 110 | R>H | No | SGRP | |
| s03-160038 | 111 | N>S | No | SGRP | |
| s03-159770 | 200 | L>F | No | SGRP | |
| s03-159736 | 212 | G>S | No | SGRP | |
| s03-159685 | 229 | D>N | No | SGRP | |
| s03-159597 | 258 | R>H | No | SGRP | |
| s03-159543 | 276 | I>N | No | SGRP | |
| s03-159532 | 280 | D>N | No | SGRP | |
| s03-159525 | 282 | E>G | No | SGRP | |
| s03-159153 | 406 | G>D | No | SGRP | |
| s03-158952 | 473 | Y>C | No | SGRP | |
| s03-158631 | 580 | S>N | No | SGRP | |
| s03-158623 | 583 | A>T | No | SGRP |
No associated diseases with P25351
1 regional properties for P25351
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 19 - 570 | IPR020846 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| fungal-type vacuole membrane | The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARQKLTFKE | QMDGFPWVQL | VVVSLVRFSE | PIAFSSLFPY | VYFMVRDFNI | APNDAQVSKY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SGYLSSSFAL | CQVISAYHWG | RFSEKHGRKI | TLTCGLIGTS | VSLLILGFSR | NFYQALVARS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LMGLLNGNVG | VIRTIIGEIA | TERKHQALAF | STMPLLFQFG | AVVGPMIGGF | LVFRDGTMNE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VPLWFPHFAK | RIIRSYPYAL | PNVVVCMFLM | FGLTNATLFL | EETHPAFKDR | RDYGLEVGDF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IKKNIFGIQP | KRRPWQKRIQ | DDSENIHHRN | ENVNSIRGQD | SEEDENSPLV | NTTNDDDTES |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IQSIDPILTR | RQSVGLIRTY | SLHEPTDAVH | ANIDTAPDGC | KESSIFHHVF | HTKVFYPISV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NFIMALHLIV | YNEFLPVFLA | YDLAVDPENP | KKLASKFPWK | ISGGIGYEPE | QTGTLLSTTG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IFGCFVVIFI | FPIVDRNFDC | LTIFRTLVKL | YPIMYVMVPY | VVFLQNERIP | SWYTVVYLYI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ITGIKTFCGA | LTSPQIMLLI | HNSSPLSCRS | VINGATISIS | ASARFIGPLV | WGYIMSWSQQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| NDVAWVSWWS | LSLFCMVALY | QSYKIAPIDD | NENELHGQGS | EDAYNSQSQS | SDLRMAHRSS |
| 610 | |||||
| LSSLSNQRCT | T |