P24647

PR
Gene name
IE2 (ORF151)
Protein name
E3 ubiquitin-protein ligase IE2
Names
Immediate-early protein IE2, RING-type E3 ubiquitin transferase IE2
Species
Autographa californica nuclear polyhedrosis virus (AcMNPV)
KEGG Pathway
vg:1403984
EC number
2.3.2.27: Aminoacyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-90 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P24647

Entry ID Method Resolution Chain Position Source

No variants for P24647

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P24647

No associated diseases with P24647

3 regional properties for P24647

Type Name Position InterPro Accession
domain Zinc finger, RING-type 207 - 251 IPR001841
conserved_site Zinc finger, RING-type, conserved site 230 - 239 IPR017907
domain Zinc finger, C3HC4 RING-type 207 - 251 IPR018957

Functions

Description
EC Number 2.3.2.27 Aminoacyltransferases
Subcellular Localization
  • Host nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
metal ion binding Binding to a metal ion.
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

2 GO annotations of biological process

Name Definition
modulation by virus of host protein ubiquitination Any process in which a virus modulates the frequency, rate or extent of protein ubiquitination in the host organism. Ubiquitination is the process in which one or more ubiquitin groups are added to a protein.
regulation of viral transcription Any process that modulates the frequency, rate or extent of the transcription of the viral genome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRQINAATP SSSRRHRLSL SRRRINFTTS PEAQPSSSSR SQPSSSSRSH RRQERRQEQR
70 80 90 100 110 120
VSEENVQIIG NVNEPLTRTY HRQGVTYYVH GQVNISNDDP LLSQEDDVIL INSENVDRER
130 140 150 160 170 180
FPDITAQQYQ DNIASETAAQ RALQRGLDLE AQLMNEIAPR SPTYSPSYSP NYVIPQSPDL
190 200 210 220 230 240
FASPQSPQPQ QQQQQQSEPE EEVEVSCNIC FTTFKDTKNV NSSFVTSIHC NHAVCFKCYV
250 260 270 280 290 300
KIIMDNSVYK CFCSATSSDC RVYNKHGYVE FMPINVTRNQ DSIKQHWREL LENNTVNNHT
310 320 330 340 350 360
TDLNYVEQLQ KELSELRAKT SQVEHKMTML NSDYIMLKHK HAVAELDLQK ANYDLQESTK
370 380 390 400
KSEELQSTVN NLQEQLRKQV AESQAKFSEF ERSNSDLVSK LQTVMSRR