P24507

PR
Gene name
P65-C
Protein name
Synaptotagmin-C
Names
Synaptic vesicle protein O-p65-C
Species
Diplobatis ommata (Ocellated electric ray) (Discopyge ommata)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

91-271 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P24507

Entry ID Method Resolution Chain Position Source
AF-P24507-F1 Predicted AlphaFoldDB

No variants for P24507

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P24507

No associated diseases with P24507

6 regional properties for P24507

Type Name Position InterPro Accession
domain C2 domain 236 - 357 IPR000008-1
domain C2 domain 368 - 501 IPR000008-2
domain Synaptotagmin 240 - 255 IPR001565-1
domain Synaptotagmin 255 - 268 IPR001565-2
domain Synaptotagmin 310 - 325 IPR001565-3
domain Synaptotagmin 330 - 340 IPR001565-4

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein
  • Synapse
  • Synaptic vesicles in neurons
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
anchoring junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
synaptic vesicle membrane The lipid bilayer surrounding a synaptic vesicle.

1 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
calcium-ion regulated exocytosis The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSGDGEDELC RNALALVNEL CFSVRGNHNN EKCIEFSYLL RDRDRTRHIE TDISVSLLSV
70 80 90 100 110 120
IVTFCGIVLL GVSLFVSWKL CWIPWRDKGL NPQRRDSQHH PHQHLHHHHS HFTDLTVERV
130 140 150 160 170 180
DCGPEMPERS YLDLESYPES GIKLSQTSPD IPVDTSSGSK ENNIPNAHSQ QQVSAPPPAT
190 200 210 220 230 240
RFNSLPRPIP QQLSSPEFGT QADEKVEQVT SIGQIKPELY KQRSIDTEAK KHQKVNCGRI
250 260 270 280 290 300
NFMLRYTYTT EQLVVKILKA LDLPAKDANG FSDPYVKIYL LPDRKKKFQT KVHRKTLNPI
310 320 330 340 350 360
FNETFQFNVP FNELQNRKLH FSVYDFDRFS RHDLIGQVVL DNLLEFSDFS EDTTIWRDIL
370 380 390 400 410 420
EATSEKADLG EINFSLCYLP TAGRLTITII KATNLKAMDL TGFSDPYVKA SLICDERRLK
430 440 450 460 470 480
KRKTSIKKNT LNPVYNEALV FDIPNENMEH VNVIIAVMDY DCIGHNEVIG MCRVGNATDG
490 500 510 520 530
PGREHWNEML ANPRKPIEQW HQLIEEKVMN SYMTKSFAAG TGATKPVTIV VESPHSV