Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P24011

Entry ID Method Resolution Chain Position Source
AF-P24011-F1 Predicted AlphaFoldDB

No variants for P24011

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P24011

No associated diseases with P24011

6 regional properties for P24011

Type Name Position InterPro Accession
binding_site Copper centre Cu(A) 174 - 228 IPR001505
domain Cytochrome c oxidase subunit II-like C-terminal 128 - 246 IPR002429
domain Cytochrome c-like domain 257 - 352 IPR009056
domain Cytochrome C oxidase subunit II, transmembrane domain 20 - 118 IPR011759
domain Cytochrome c oxidase, subunit II 31 - 244 IPR014222
domain Caa3-type Cytochrome c oxidase subunit II, cupredoxin domain 130 - 235 IPR034236

Functions

Description
EC Number 7.1.1.9 Hydron translocation or charge separation linked to oxidoreductase reactions
Subcellular Localization
  • Cell membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
respirasome The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

3 GO annotations of molecular function

Name Definition
copper ion binding Binding to a copper (Cu) ion.
cytochrome-c oxidase activity Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.

1 GO annotations of biological process

Name Definition
ATP synthesis coupled electron transport The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVKHWRLILL LALVPLLLSG CGKPFLSTLK PAGEVADKQY DLTVLSTLIM VVVVAVVSVI
70 80 90 100 110 120
FFYVIVRFRR SRVGENTIPK QVEGNKFLEI TWTVIPILLL IILVIPVVLY TLELADTSPM
130 140 150 160 170 180
DKKGRKAEDA LVVNVRANLY WWEFEYPDYG IITSQELIVP TDQRVYFNLK ASDVKHSFWI
190 200 210 220 230 240
PSVGGKLDTN TDNENKFFLT FDSKRSKEAG DMFFGKCAEL CGPSHALMDF KVKTMSAKEF
250 260 270 280 290 300
QGWTKEMKNY KSTAESDLAK QGEELFKEKN CLSCHAVEPN DKRAEAARTA PNLATFGERT
310 320 330 340 350
KVAGVKEANK ENVKAWLKDP DSIKPGNKMT GTYPKLSDSE TNALYEYLKG LKAESK