P23796
Gene name |
RIT1 (YMR283C, YM8021.09C) |
Protein name |
tRNA A64-2'-O-ribosylphosphate transferase |
Names |
Initiator tRNA phosphoribosyl-transferase |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YMR283C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P23796
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P23796-F1 | Predicted | AlphaFoldDB |
14 variants for P23796
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s13-836847 | 7 | K>R | No | SGRP | |
| s13-836844 | 8 | R>K | No | SGRP | |
| s13-836659 | 70 | I>V | No | SGRP | |
| s13-836650 | 73 | E>K | No | SGRP | |
| s13-836385 | 161 | V>D | No | SGRP | |
| s13-836365 | 168 | Y>H | No | SGRP | |
| s13-836275 | 198 | I>V | No | SGRP | |
| s13-836258 | 203 | K>N | No | SGRP | |
| s13-836241 | 209 | M>T | No | SGRP | |
| s13-836161 | 236 | V>L | No | SGRP | |
| s13-835968 | 300 | Y>F | No | SGRP | |
| s13-835675 | 398 | P>S | No | SGRP | |
| s13-835669 | 400 | I>F | No | SGRP | |
| s13-835544 | 441 | M>I | No | SGRP |
No associated diseases with P23796
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| pentosyltransferase activity | Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor). |
| tRNA A64-2'-O-ribosylphosphate transferase activity | Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| charged-tRNA amino acid modification | The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVSRLSKRYR | SRVQFSISVM | DENIYLSLSQ | INKDIRKENK | SVRNRLQSIL | LDNKFLQDRV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IPIFPHYPLI | PNERCGLWYC | NPSSFKQTSY | FKSTDGHVNQ | WDFSTRRLNF | HLLETIRDNK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GIIIVDSTRR | GKKIPDALSK | TVPIWCAVLN | TLMLQETEKN | VAIDKVLYLP | PETVPKSEYD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MIKRKIPELV | AKLQKLNIID | SKKLNELFMG | KLLRPIWVHP | GSSLLDHSVD | YFTGEVQEYE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AWETPEDQNI | IPIILCTVSY | QAQDGMDKRY | GFTYVQGAAD | DHELWSFGLD | SNMFWAHIEY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LGDASYSDDQ | LHDYIMDLAA | AKLRNQCYIQ | DKGSLDEVFG | NIDKITNEIS | LGKVSSGLTI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NKNLKQKLKS | EYGKVIIFSN | SVTVAEDTDD | EEESGTDPFI | SIYKLQSGDK | KSSKALRSTF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PRIHGEIQSL | FTNRDEKIKP | MLICCNTGTD | MSIGVILSIL | CTKYTEEWML | TSELPDISKL |
| 490 | 500 | 510 | |||
| IVRKHLTKLI | SHLKGRNVNP | SRATLNSVNS | FLM |