P23724

PR
Gene name
PRE7 (PRS3, PTS1, YBL041W, YBL0407)
Protein name
Proteasome subunit beta type-6
Names
Multicatalytic endopeptidase complex subunit C5, Proteasome component C5
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YBL041W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

323 structures for P23724

Entry ID Method Resolution Chain Position Source
1FNT X-ray 320 A M/a 20-240 PDB
1G0U X-ray 240 A L/Z 1-241 PDB
1G65 X-ray 225 A L/Z 20-241 PDB
1JD2 X-ray 300 A L/S 20-241 PDB
1RYP X-ray 190 A 1/M 20-241 PDB
1Z7Q X-ray 322 A M/a 20-241 PDB
2F16 X-ray 280 A L/Z 20-241 PDB
2FAK X-ray 280 A L/Z 20-241 PDB
2GPL X-ray 281 A L/Z 20-241 PDB
2ZCY X-ray 290 A L/Z 1-241 PDB
3BDM X-ray 270 A L/Z 1-241 PDB
3D29 X-ray 260 A L/Z 20-241 PDB
3DY3 X-ray 281 A L/Z 20-241 PDB
3DY4 X-ray 280 A L/Z 20-241 PDB
3E47 X-ray 300 A L/Z 20-241 PDB
3GPJ X-ray 270 A L/Z 20-241 PDB
3GPT X-ray 241 A L/Z 20-241 PDB
3GPW X-ray 250 A L/Z 20-241 PDB
3HYE X-ray 250 A L/Z 20-241 PDB
3JCO EM 480 A 1/8 1-241 PDB
3JCP EM 460 A 1/8 1-241 PDB
3MG0 X-ray 268 A L/Z 20-241 PDB
3MG4 X-ray 311 A L/Z 20-241 PDB
3MG6 X-ray 260 A L/Z 1-241 PDB
3MG7 X-ray 278 A L/Z 1-241 PDB
3MG8 X-ray 259 A L/Z 1-241 PDB
3NZJ X-ray 240 A L/Z 1-241 PDB
3NZW X-ray 250 A L/Z 1-241 PDB
3NZX X-ray 270 A L/Z 1-241 PDB
3OEU X-ray 260 A L/Z 20-241 PDB
3OEV X-ray 285 A L/Z 20-241 PDB
3OKJ X-ray 270 A L/Z 20-241 PDB
3SDI X-ray 265 A L/Z 20-241 PDB
3SDK X-ray 270 A L/Z 20-241 PDB
3SHJ X-ray 280 A L/Z 20-241 PDB
3TDD X-ray 270 A L/Z 20-241 PDB
3UN4 X-ray 340 A L/Z 20-241 PDB
3UN8 X-ray 270 A L/Z 20-241 PDB
3WXR X-ray 315 A 1/M 1-241 PDB
4CR2 EM 770 A 6 1-241 PDB
4CR3 EM 930 A 6 1-241 PDB
4CR4 EM 880 A 6 1-241 PDB
4EU2 X-ray 251 A 1/M 20-241 PDB
4FZC X-ray 280 A L/Z 20-241 PDB
4FZG X-ray 300 A L/Z 20-241 PDB
4G4S X-ray 249 A M 20-241 PDB
4GK7 X-ray 280 A L/Z 20-241 PDB
4HNP X-ray 280 A L/Z 20-241 PDB
4HRC X-ray 280 A L/Z 20-241 PDB
4HRD X-ray 280 A L/Z 20-241 PDB
4INR X-ray 270 A L/Z 20-241 PDB
4INT X-ray 290 A L/Z 20-241 PDB
4INU X-ray 310 A L/Z 20-241 PDB
4J70 X-ray 280 A L/Z 20-241 PDB
4JSQ X-ray 280 A L/Z 20-241 PDB
4JSU X-ray 290 A L/Z 20-241 PDB
4JT0 X-ray 310 A L/Z 20-241 PDB
4LQI X-ray 270 A L/Z 20-241 PDB
4LTC X-ray 250 A L/Z 20-241 PDB
4NNN X-ray 250 A L/Z 20-241 PDB
4NNW X-ray 260 A L/Z 20-241 PDB
4NO1 X-ray 250 A L/Z 20-241 PDB
4NO6 X-ray 300 A L/Z 20-241 PDB
4NO8 X-ray 270 A L/Z 20-241 PDB
4NO9 X-ray 290 A L/Z 20-241 PDB
4Q1S X-ray 260 A L/Z 20-241 PDB
4QBY X-ray 300 A L/Z 20-241 PDB
4QLQ X-ray 240 A L/Z 20-241 PDB
4QLS X-ray 280 A L/Z 20-241 PDB
4QLT X-ray 280 A L/Z 20-241 PDB
4QLU X-ray 280 A L/Z 20-241 PDB
4QLV X-ray 290 A L/Z 20-241 PDB
4QUX X-ray 300 A L/Z 20-241 PDB
4QUY X-ray 280 A L/Z 20-241 PDB
4QV0 X-ray 310 A L/Z 20-241 PDB
4QV1 X-ray 250 A L/Z 20-241 PDB
4QV3 X-ray 300 A L/Z 20-241 PDB
4QV4 X-ray 270 A L/Z 20-241 PDB
4QV5 X-ray 270 A L/Z 20-241 PDB
4QV6 X-ray 280 A L/Z 20-241 PDB
4QV7 X-ray 260 A L/Z 20-241 PDB
4QV8 X-ray 290 A L/Z 20-241 PDB
4QV9 X-ray 260 A L/Z 20-241 PDB
4QVL X-ray 280 A L/Z 20-241 PDB
4QVM X-ray 280 A L/Z 20-241 PDB
4QVN X-ray 290 A L/Z 20-241 PDB
4QVP X-ray 230 A L/Z 20-241 PDB
4QVQ X-ray 260 A L/Z 20-241 PDB
4QVV X-ray 280 A L/Z 20-241 PDB
4QVW X-ray 300 A L/Z 20-241 PDB
4QVY X-ray 251 A L/Z 20-241 PDB
4QW0 X-ray 290 A L/Z 20-241 PDB
4QW1 X-ray 290 A L/Z 20-241 PDB
4QW3 X-ray 290 A L/Z 20-241 PDB
4QW4 X-ray 280 A L/Z 20-241 PDB
4QW5 X-ray 300 A L/Z 20-241 PDB
4QW6 X-ray 290 A L/Z 20-241 PDB
4QW7 X-ray 270 A L/Z 20-241 PDB
4QWF X-ray 300 A L/Z 20-241 PDB
4QWG X-ray 260 A L/Z 20-241 PDB
4QWI X-ray 260 A L/Z 20-241 PDB
4QWJ X-ray 290 A L/Z 20-241 PDB
4QWK X-ray 280 A L/Z 20-241 PDB
4QWL X-ray 260 A L/Z 20-241 PDB
4QWR X-ray 290 A L/Z 20-241 PDB
4QWS X-ray 300 A L/Z 20-241 PDB
4QWU X-ray 300 A L/Z 20-241 PDB
4QWX X-ray 290 A L/Z 20-241 PDB
4QXJ X-ray 280 A L/Z 20-241 PDB
4QZ0 X-ray 300 A L/Z 20-241 PDB
4QZ1 X-ray 300 A L/Z 20-241 PDB
4QZ2 X-ray 270 A L/Z 20-241 PDB
4QZ3 X-ray 280 A L/Z 20-241 PDB
4QZ4 X-ray 300 A L/Z 20-241 PDB
4QZ5 X-ray 280 A L/Z 20-241 PDB
4QZ6 X-ray 290 A L/Z 20-241 PDB
4QZ7 X-ray 280 A L/Z 20-241 PDB
4QZW X-ray 300 A L/Z 20-241 PDB
4QZX X-ray 260 A L/Z 20-241 PDB
4QZZ X-ray 290 A L/Z 20-241 PDB
4R00 X-ray 280 A L/Z 20-241 PDB
4R02 X-ray 250 A L/Z 20-241 PDB
4R17 X-ray 210 A L/Z 20-241 PDB
4R18 X-ray 240 A L/Z 20-241 PDB
4RUR X-ray 250 A L/Z 20-241 PDB
4V7O X-ray 300 A A3/AQ/B1/BM 20-241 PDB
4X6Z X-ray 270 A 1/M 1-241 PDB
4Y69 X-ray 290 A L/Z 20-241 PDB
4Y6A X-ray 260 A L/Z 20-241 PDB
4Y6V X-ray 280 A L/Z 20-241 PDB
4Y6Z X-ray 270 A L/Z 20-241 PDB
4Y70 X-ray 240 A L/Z 20-241 PDB
4Y74 X-ray 270 A L/Z 20-241 PDB
4Y75 X-ray 280 A L/Z 20-241 PDB
4Y77 X-ray 250 A L/Z 20-241 PDB
4Y78 X-ray 280 A L/Z 20-241 PDB
4Y7W X-ray 250 A L/Z 20-241 PDB
4Y7X X-ray 260 A L/Z 20-241 PDB
4Y7Y X-ray 240 A L/Z 20-241 PDB
4Y80 X-ray 250 A L/Z 20-241 PDB
4Y81 X-ray 280 A L/Z 20-241 PDB
4Y82 X-ray 280 A L/Z 20-241 PDB
4Y84 X-ray 270 A L/Z 20-241 PDB
4Y8G X-ray 260 A L/Z 20-241 PDB
4Y8H X-ray 250 A L/Z 20-241 PDB
4Y8I X-ray 260 A L/Z 20-241 PDB
4Y8J X-ray 270 A L/Z 20-241 PDB
4Y8K X-ray 260 A L/Z 20-241 PDB
4Y8L X-ray 240 A L/Z 20-241 PDB
4Y8M X-ray 280 A L/Z 20-241 PDB
4Y8N X-ray 260 A L/Z 20-241 PDB
4Y8O X-ray 270 A L/Z 20-241 PDB
4Y8P X-ray 280 A L/Z 20-241 PDB
4Y8Q X-ray 260 A L/Z 20-241 PDB
4Y8R X-ray 270 A L/Z 20-241 PDB
4Y8S X-ray 270 A L/Z 20-241 PDB
4Y8T X-ray 270 A L/Z 20-241 PDB
4Y8U X-ray 290 A L/Z 20-241 PDB
4Y9Y X-ray 280 A L/Z 20-241 PDB
4Y9Z X-ray 280 A L/Z 20-241 PDB
4YA0 X-ray 280 A L/Z 20-241 PDB
4YA1 X-ray 290 A L/Z 20-241 PDB
4YA2 X-ray 270 A L/Z 20-241 PDB
4YA3 X-ray 270 A L/Z 20-241 PDB
4YA4 X-ray 290 A L/Z 20-241 PDB
4YA5 X-ray 250 A L/Z 20-241 PDB
4YA7 X-ray 270 A L/Z 20-241 PDB
4YA9 X-ray 270 A L/Z 20-241 PDB
4Z1L X-ray 300 A L/Z 20-241 PDB
5A5B EM 950 A 6 1-241 PDB
5AHJ X-ray 280 A L/Z 20-241 PDB
5BOU X-ray 260 A L/Z 20-241 PDB
5BXL X-ray 280 A L/Z 20-241 PDB
5BXN X-ray 280 A L/Z 20-241 PDB
5CGF X-ray 280 A L/Z 20-241 PDB
5CGG X-ray 290 A L/Z 20-241 PDB
5CGH X-ray 250 A L/Z 20-241 PDB
5CGI X-ray 280 A L/Z 20-241 PDB
5CZ4 X-ray 230 A L/Z 20-241 PDB
5CZ5 X-ray 280 A L/Z 20-241 PDB
5CZ6 X-ray 270 A L/Z 20-241 PDB
5CZ7 X-ray 250 A L/Z 20-241 PDB
5CZ8 X-ray 280 A L/Z 20-241 PDB
5CZ9 X-ray 290 A L/Z 20-241 PDB
5CZA X-ray 250 A L/Z 20-241 PDB
5D0S X-ray 250 A L/Z 20-241 PDB
5D0T X-ray 260 A L/Z 20-241 PDB
5D0V X-ray 290 A L/Z 20-241 PDB
5D0W X-ray 280 A L/Z 20-241 PDB
5D0X X-ray 260 A L/Z 20-241 PDB
5D0Z X-ray 290 A L/Z 20-241 PDB
5DKI X-ray 280 A L/Z 20-241 PDB
5DKJ X-ray 280 A L/Z 20-241 PDB
5FG7 X-ray 270 A L/Z 20-241 PDB
5FG9 X-ray 260 A L/Z 20-241 PDB
5FGA X-ray 270 A L/Z 20-241 PDB
5FGD X-ray 280 A L/Z 20-241 PDB
5FGE X-ray 260 A L/Z 20-241 PDB
5FGF X-ray 260 A L/Z 20-241 PDB
5FGG X-ray 270 A L/Z 20-241 PDB
5FGH X-ray 280 A L/Z 20-241 PDB
5FGI X-ray 290 A L/Z 20-241 PDB
5FHS X-ray 270 A L/Z 20-241 PDB
5JHR X-ray 290 A L/Z 20-241 PDB
5JHS X-ray 300 A L/Z 20-241 PDB
5L52 X-ray 270 A L/Z 20-241 PDB
5L54 X-ray 280 A L/Z 20-241 PDB
5L55 X-ray 290 A L/Z 20-241 PDB
5L5A X-ray 240 A L/Z 20-241 PDB
5L5B X-ray 280 A PDB
5L5D X-ray 280 A PDB
5L5E X-ray 290 A PDB
5L5F X-ray 250 A PDB
5L5H X-ray 260 A PDB
5L5I X-ray 290 A PDB
5L5J X-ray 290 A PDB
5L5O X-ray 260 A PDB
5L5P X-ray 280 A PDB
5L5Q X-ray 280 A PDB
5L5R X-ray 290 A PDB
5L5S X-ray 260 A PDB
5L5T X-ray 290 A PDB
5L5U X-ray 260 A PDB
5L5V X-ray 270 A PDB
5L5W X-ray 280 A PDB
5L5X X-ray 290 A PDB
5L5Y X-ray 270 A PDB
5L5Z X-ray 270 A PDB
5L60 X-ray 270 A PDB
5L61 X-ray 280 A PDB
5L62 X-ray 280 A PDB
5L63 X-ray 270 A PDB
5L64 X-ray 270 A PDB
5L65 X-ray 290 A PDB
5L66 X-ray 280 A PDB
5L67 X-ray 260 A PDB
5L68 X-ray 280 A PDB
5L69 X-ray 270 A PDB
5L6A X-ray 280 A PDB
5L6B X-ray 260 A PDB
5L6C X-ray 260 A PDB
5LAI X-ray 250 A L/Z 20-241 PDB
5LAJ X-ray 290 A L/Z 20-241 PDB
5LTT X-ray 270 A L/Z 20-241 PDB
5M2B X-ray 270 A PDB
5MP9 EM 410 A 6/m 1-241 PDB
5MPA EM 450 A 6/m 1-241 PDB
5MPB EM 780 A 6/m 1-241 PDB
5MPC EM 770 A 6/m 1-241 PDB
5NIF X-ray 300 A 1/M 1-241 PDB
5WVI EM 630 A 6/e 1-241 PDB
5WVK EM 420 A 6/e 1-241 PDB
6EF3 EM 417 A 6 1-241 PDB
6FVT EM 410 A 6/m 20-241 PDB
6FVU EM 450 A 6/m 20-241 PDB
6FVV EM 540 A 6/m 20-241 PDB
6FVW EM 450 A 6/m 20-241 PDB
6FVX EM 490 A 6/m 20-241 PDB
6FVY EM 610 A 6/m 20-241 PDB
6G7F X-ray 270 A L/Z 20-241 PDB
6G8M X-ray 270 A L/Z 20-241 PDB
6G8N X-ray 300 A L/Z 20-241 PDB
6GOP X-ray 290 A L/Z 20-241 PDB
6H39 X-ray 250 A L/Z 20-241 PDB
6HTB X-ray 270 A L/Z 20-241 PDB
6HTC X-ray 280 A L/Z 20-241 PDB
6HTD X-ray 300 A L/Z 20-241 PDB
6HTP X-ray 300 A L/Z 20-241 PDB
6HTR X-ray 260 A L/Z 20-241 PDB
6HUB X-ray 290 A L/Z 20-241 PDB
6HUC X-ray 300 A L/Z 20-241 PDB
6HUQ X-ray 300 A L/Z 20-241 PDB
6HUU X-ray 280 A L/Z 20-241 PDB
6HUV X-ray 310 A L/Z 20-241 PDB
6HV3 X-ray 270 A L/Z 20-241 PDB
6HV4 X-ray 300 A L/Z 20-241 PDB
6HV5 X-ray 300 A L/Z 20-241 PDB
6HV7 X-ray 340 A L/Z 20-241 PDB
6HVA X-ray 290 A L/Z 20-241 PDB
6HVR X-ray 270 A L/Z 20-241 PDB
6HVS X-ray 310 A L/Z 20-241 PDB
6HVT X-ray 290 A L/Z 20-241 PDB
6HVU X-ray 290 A L/Z 20-241 PDB
6HVV X-ray 270 A L/Z 20-241 PDB
6HVW X-ray 300 A L/Z 20-241 PDB
6HVX X-ray 280 A L/Z 20-241 PDB
6HVY X-ray 270 A L/Z 20-241 PDB
6HW0 X-ray 280 A L/Z 20-241 PDB
6HW3 X-ray 260 A L/Z 20-241 PDB
6HW4 X-ray 290 A L/Z 20-241 PDB
6HW5 X-ray 290 A L/Z 20-241 PDB
6HW6 X-ray 270 A L/Z 20-241 PDB
6HW7 X-ray 270 A L/Z 20-241 PDB
6HW8 X-ray 280 A L/Z 20-241 PDB
6HW9 X-ray 280 A L/Z 20-241 PDB
6HWA X-ray 280 A L/Z 20-241 PDB
6HWB X-ray 260 A L/Z 20-241 PDB
6HWC X-ray 280 A L/Z 20-241 PDB
6HWD X-ray 280 A L/Z 20-241 PDB
6HWE X-ray 230 A L/Z 20-241 PDB
6HWF X-ray 250 A L/Z 20-241 PDB
6J2C EM 700 A 6/e 1-241 PDB
6J2N EM 750 A 6/e 1-241 PDB
6J2Q EM 380 A 6/e 1-241 PDB
6J2X EM 380 A 6/e 1-241 PDB
6J30 EM 450 A 6/e 1-241 PDB
6ZOU X-ray 290 A L/Z 20-241 PDB
6ZP6 X-ray 280 A L/Z 20-241 PDB
6ZP8 X-ray 300 A L/Z 20-241 PDB
7LS5 EM 274 A 1/M 1-241 PDB
7LS6 EM 317 A M 1-241 PDB
7O2L X-ray 300 A L/Z 20-241 PDB
7QO3 EM 610 A 6/m 1-241 PDB
7QO5 EM 600 A 6/m 1-241 PDB
7TEJ EM 274 A 1/M 1-241 PDB
7TEO EM 297 A 1/M 1-241 PDB
8BW1 X-ray 325 A L/Z 20-241 PDB
8OHZ X-ray 265 A L/Z 20-241 PDB
8OI1 X-ray 295 A L/Z 20-241 PDB
8OLR X-ray 280 A L/Z 20-241 PDB
8T08 EM 300 A M/d 1-241 PDB
8T0M EM 240 A M/a 1-241 PDB
AF-P23724-F1 Predicted AlphaFoldDB

3 variants for P23724

Variant ID(s) Position Change Description Diseaes Association Provenance
s02-141295 16 P>A No SGRP
s02-141548 100 D>G No SGRP
s02-141790 181 P>A No SGRP

No associated diseases with P23724

No regional properties for P23724

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P23724

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
proteasome complex A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
proteasome core complex A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
proteasome core complex, beta-subunit complex The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
proteasomal ubiquitin-independent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.
proteasome-mediated ubiquitin-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATIASEYSS EASNTPIEHQ FNPYGDNGGT ILGIAGEDFA VLAGDTRNIT DYSINSRYEP
70 80 90 100 110 120
KVFDCGDNIV MSANGFAADG DALVKRFKNS VKWYHFDHND KKLSINSAAR NIQHLLYGKR
130 140 150 160 170 180
FFPYYVHTII AGLDEDGKGA VYSFDPVGSY EREQCRAGGA AASLIMPFLD NQVNFKNQYE
190 200 210 220 230 240
PGTNGKVKKP LKYLSVEEVI KLVRDSFTSA TERHIQVGDG LEILIVTKDG VRKEFYELKR
D