P23316

PR
Gene name
CHS1
Protein name
Chitin synthase 1
Names
Chitin-UDP acetyl-glucosaminyl transferase 1
Species
Candida albicans (Yeast)
KEGG Pathway
EC number
2.4.1.16: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-93 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P23316

Entry ID Method Resolution Chain Position Source
AF-P23316-F1 Predicted AlphaFoldDB

No variants for P23316

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P23316

No associated diseases with P23316

2 regional properties for P23316

Type Name Position InterPro Accession
conserved_site Heat shock protein 70, conserved site 137 - 150 IPR018181-1
conserved_site Heat shock protein 70, conserved site 278 - 292 IPR018181-2

Functions

Description
EC Number 2.4.1.16 Hexosyltransferases
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
chitin synthase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).

2 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
chitin biosynthetic process The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHNINNGYVP NREKTITKRK VRLVGGKAGN LVLENPVPTE LRKVLTRTES PFGEFTNMTY
70 80 90 100 110 120
TACTSQPDTF SAEGFTLRAA KYGRETEIVI CITMYNEDEV AFARTMHGVM KNIAHLCSRH
130 140 150 160 170 180
KSKIWGKDSW KKVQVIIVAD GRNKVQQSVL ELLTATGCYQ ENLARPYVNN SKVNAHLFEY
190 200 210 220 230 240
TTQISIDENL KFKGDEKNLA PVQVLFCLKE SNQKKINSHR WLFNAFCPVL DPNVIVLLDV
250 260 270 280 290 300
GTKPDNHAIY NLWKAFDRDS NVAGAAGEIK AMKGKGWINL TNPLVASQNF EYKLSNILDK
310 320 330 340 350 360
PLESLFGYIS VLPGALSAYR YIALKNHDDG TGPLASYFKG EDLLCSHDKD KENTKANFFE
370 380 390 400 410 420
ANMYLAEDRI LCWELVSKRN DNWVLKFVKS ATGETDVPET IAEFLSQRRR WINGAFFAAL
430 440 450 460 470 480
YSLYHFRKIW TTDHSYARKF WLHVEEFIYQ LVSLLFSFFS LSNFYLTFYF LTGSLVSYKS
490 500 510 520 530 540
LGKKGGFWIF TLFNYLCIGV LTSLFIVSIG NRPHASKNIF KTLIILLTIC ALYALVVGFV
550 560 570 580 590 600
FVINTIATFG TGGTSTYVLV SIVVSLLSTY GLYTLMSILY LDPWHMLTCS VQYFLMIPSY
610 620 630 640 650 660
TCTLQIFAFC NTHDVSWGTK GDNNPKEDLS NQYIIEKNAS GEFEAVIVDT NIDEDYLETL
670 680 690 700 710 720
YNIRSKRSNK KVALGHSEKT PLDGDDYAKD VRTRVVLFWM IANLVFIMTM VQVYEPGDTG
730 740 750 760 770
RNIYLAFILW AVAVLALVRA IGSLGYLIQT YARFFVESKS KWMKRGYTAP SHNPLN