P23057

PR
Gene name
P/V
Protein name
Non-structural protein V
Names
Species
Human parainfluenza 2 virus (strain Toshiba) (HPIV-2)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-203 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P23057

Entry ID Method Resolution Chain Position Source

No variants for P23057

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P23057

No associated diseases with P23057

2 regional properties for P23057

Type Name Position InterPro Accession
domain Paramyxovirinae protein V, zinc-binding domain 179 - 222 IPR024279
domain Phosphoprotein P soyouz module 6 - 60 IPR025909

Functions

Description
EC Number
Subcellular Localization
  • Host nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
host cell cytoplasm The cytoplasm of a host cell.

1 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.

3 GO annotations of biological process

Name Definition
suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2).
suppression by virus of host type I interferon-mediated signaling pathway Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEEPTYTTE QVDELIHAGL GTVDFFLSRP IDAQSSLGKG SIPPGVTAVL TSAAETKSKP
70 80 90 100 110 120
VAAGPVKPRR KKVISNTTPY TIADNIPPEK LPINTPIPNP LLPLARPHGK MTDIDIVTGN
130 140 150 160 170 180
ITEGSYKGVE LAKLGKQTLL TRFTSNEPVS SAGSAQDPNF KRGGANRERA RGNHRREWSI
190 200 210 220
AWVGDQVKVF EWCNPRCAPV TASARKFTCT CGSCPSICGE CEGDH