P23049

PR
Gene name
V-SEA
Protein name
Tyrosine-protein kinase transforming protein SEA
Names
Species
Avian erythroblastosis virus (strain S13)
KEGG Pathway
EC number
2.7.10.2: Protein-tyrosine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-79 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P23049

Entry ID Method Resolution Chain Position Source

No variants for P23049

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P23049

No associated diseases with P23049

5 regional properties for P23049

Type Name Position InterPro Accession
domain Protein kinase domain 60 - 323 IPR000719
domain Serine-threonine/tyrosine-protein kinase, catalytic domain 63 - 318 IPR001245
active_site Tyrosine-protein kinase, active site 182 - 194 IPR008266
binding_site Protein kinase, ATP binding site 66 - 92 IPR017441
domain Tyrosine-protein kinase, catalytic domain 60 - 319 IPR020635

Functions

Description
EC Number 2.7.10.2 Protein-tyrosine kinases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
non-membrane spanning protein tyrosine kinase activity Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
ADSPGLARPH AHFASAGADA AGGGSPVLLL RTTSCCLEDL RPELLEEVKD ILIPEERLIT
70 80 90 100 110 120
HRSRVIGRGH FGSVYHGTYM DPLLGNLHCA VKSLHRITYL EEVEEFLREG ILMKGFHHPQ
130 140 150 160 170 180
VLSLLGVCLP RHGLPLVVLP YMRHGDLRHF VRAQERSPTV KELIGFGLQV ALGMEYLAQK
190 200 210 220 230 240
KFVHRDLAAR NCMLDETLTV KVADFGLARD VFGKEYYSIR QHRHAKLPVR WMALESLQTQ
250 260 270 280 290 300
KFTTKSDVWS FGVLMWELLT RGASPYPEVD PYDMARYLLR GRRLPQPQPC PDTLYGVMLS
310 320 330 340 350 360
CWAPTPEERP SFSGLVCELE RVLASLEGEH YINMAVTYVN LESGPPFPPA PRGQLPDSED
EEDEEEEVAE