Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P22481

Entry ID Method Resolution Chain Position Source
AF-P22481-F1 Predicted AlphaFoldDB

No variants for P22481

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P22481

No associated diseases with P22481

4 regional properties for P22481

Type Name Position InterPro Accession
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain 131 - 351 IPR000194
domain AAA+ ATPase domain 143 - 336 IPR003593
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain 8 - 74 IPR004100
active_site ATPase, alpha/beta subunit, nucleotide-binding domain, active site 342 - 351 IPR020003

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
proton-transporting ATP synthase complex, coupling factor F(o) All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins.

1 GO annotations of molecular function

Name Definition
proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGFDINWGSA LYQLLAFSVL LFFLSKFALK PLLGIMEKRE QMINEQISSA EKNRKDSEAF
70 80 90 100 110 120
IAEQRQALEQ ARMEANEIIQ NAKKLSEQQG QDIVKAARND AERIKESAVA EIQREKEQAV
130 140 150 160
SALREQVAGL SVLIATKVIE KELNEAEQEK LVQEYLKEVG EEL