Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P22122

Entry ID Method Resolution Chain Position Source
AF-P22122-F1 Predicted AlphaFoldDB

No variants for P22122

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P22122

No associated diseases with P22122

4 regional properties for P22122

Type Name Position InterPro Accession
domain Target SNARE coiled-coil homology domain 188 - 280 IPR000727
domain Syntaxin, N-terminal domain 26 - 228 IPR006011
conserved_site Syntaxin/epimorphin, conserved site 199 - 239 IPR006012
domain Syntaxin-2, SNARE motif 192 - 260 IPR028671

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

1 GO annotations of biological process

Name Definition
small GTPase mediated signal transduction The series of molecular signals in which a small monomeric GTPase relays a signal.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG KQVELALWDT
70 80 90 100 110 120
AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNI PIILVGNKKT
130 140 150 160 170 180
AGDEHTRREL AKMKQEPVKP DDAKEMGSRI KAFGYLECSA KTKEGVREVF ELASRAALQA
190
KKTKSKSPCL LL