Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

3 structures for P21678

Entry ID Method Resolution Chain Position Source
6VLI X-ray 210 A A/B/C/D 1-145 PDB
6VMH X-ray 275 A B/C 1-135 PDB
6VPE X-ray 221 A A/B 1-145 PDB

No variants for P21678

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P21678

No associated diseases with P21678

4 regional properties for P21678

Type Name Position InterPro Accession
domain Neurotransmitter-gated ion-channel transmembrane domain 240 - 371 IPR006029-1
domain Neurotransmitter-gated ion-channel transmembrane domain 375 - 446 IPR006029-2
domain Neurotransmitter-gated ion-channel ligand-binding domain 30 - 232 IPR006202
conserved_site Neurotransmitter-gated ion-channel, conserved site 153 - 167 IPR018000

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFDFQVSKHP HYDEACRAFA QRHNMAKLAE RAGMNVQTLR NKLNPEQPHQ FTPPELWLLT
70 80 90 100 110 120
DLTEDSTLVD GFLAQIHCLP CVPVNELAKD KLQSYVMRAM SELGELASGA VSDERLTTAR
130 140 150 160
KHNMIESVNS GIRMLSLSAL ALHARLQTNP AMSSVVDTMS GIGASFGLI