AiPD: Autoinhibited Protein Database

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

3-91 (Predicted disordered autoinhibitory region) PR

3-91 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
1CF9	X-ray	180 A	A/B/C/D	1-753	PDB
1GG9	X-ray	189 A	A/B/C/D	1-753	PDB
1GGE	X-ray	189 A	A/B/C/D	1-753	PDB
1GGF	X-ray	228 A	A/B/C/D	1-753	PDB
1GGH	X-ray	215 A	A/B/C/D	1-753	PDB
1GGJ	X-ray	192 A	A/B/C/D	1-753	PDB
1GGK	X-ray	226 A	A/B/C/D	1-753	PDB
1IPH	X-ray	280 A	A/B/C/D	1-753	PDB
1P7Y	X-ray	240 A	A/B/C/D	1-753	PDB
1P7Z	X-ray	221 A	A/B/C/D	1-753	PDB
1P80	X-ray	165 A	A/B/C/D	1-753	PDB
1P81	X-ray	181 A	A/B/C/D	1-753	PDB
1QF7	X-ray	220 A	A/B/C/D	1-753	PDB
1QWS	X-ray	190 A	A/B/C/D	1-753	PDB
1YE9	X-ray	280 A			PDB
3P9P	X-ray	150 A	A/B/C/D	1-753	PDB
3P9Q	X-ray	148 A	A/B/C/D	1-753	PDB
3P9R	X-ray	190 A	A/B/C/D	1-753	PDB
3P9S	X-ray	190 A	A/B/C/D	1-753	PDB
3PQ2	X-ray	179 A	A/B/C/D	1-753	PDB
3PQ3	X-ray	179 A	A/B/C/D	1-753	PDB
3PQ4	X-ray	179 A	A/B/C/D	1-753	PDB
3PQ5	X-ray	180 A	A/B/C/D	1-753	PDB
3PQ6	X-ray	180 A	A/B/C/D	1-753	PDB
3PQ7	X-ray	180 A	A/B/C/D	1-753	PDB
3PQ8	X-ray	180 A	A/B/C/D	1-753	PDB
3TTT	X-ray	158 A	A/B/C/D	1-753	PDB
3TTU	X-ray	189 A	A/B/C/D	1-753	PDB
3TTV	X-ray	145 A	A/B/C/D	1-753	PDB
3TTW	X-ray	162 A	A/B/C/D	1-753	PDB
3TTX	X-ray	174 A	A/B/C/D	1-753	PDB
3VU3	X-ray	285 A	A	1-753	PDB
4BFL	X-ray	164 A	A/B/C/D	1-753	PDB
4ENP	X-ray	150 A	A/B/C/D	1-753	PDB
4ENQ	X-ray	190 A	A/B/C/D	1-753	PDB
4ENR	X-ray	160 A	A/B/C/D	1-753	PDB
4ENS	X-ray	160 A	A/B/C/D	1-753	PDB
4ENT	X-ray	170 A	A/B/C/D	1-753	PDB
4ENU	X-ray	170 A	A/B/C/D	1-753	PDB
4ENV	X-ray	170 A	A/B/C/D	1-753	PDB
4ENW	X-ray	190 A	A/B/C/D	1-753	PDB
5BV2	X-ray	153 A	P/Q/R/S	1-753	PDB
6BY0	X-ray	293 A	A/B/C/D	1-753	PDB
6ZTV	X-ray	178 A	A/B/C/D	1-753	PDB
6ZTW	X-ray	184 A	A/B/C/D/E/F/G/H	1-753	PDB
6ZTX	X-ray	130 A	A/B/C/D	1-753	PDB
AF-P21179-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
No variants for P21179

Type	Name	Position	InterPro Accession
binding_site	Catalase haem-binding site	411 - 419	IPR002226
domain	Catalase immune-responsive domain	499 - 562	IPR010582
domain	Catalase core domain	81 - 469	IPR011614
active_site	Catalase active site	117 - 133	IPR024708
domain	Large catalase, C-terminal domain	599 - 746	IPR041399

		Description
EC Number	1.11.1.6	Peroxidases
Subcellular Localization	Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

Name	Definition
catalase activity	Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding	Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
identical protein binding	Binding to an identical protein or proteins.
iron ion binding	Binding to an iron (Fe) ion.

Name	Definition
cellular response to DNA damage stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
hydrogen peroxide catabolic process	The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
hyperosmotic response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
response to oxidative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins