P21156

PR
Gene name
cysD (b2752, JW2722)
Protein name
Sulfate adenylyltransferase subunit 2
Names
ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b2752
EC number
2.7.7.4: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

107-177 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P21156

Entry ID Method Resolution Chain Position Source
AF-P21156-F1 Predicted AlphaFoldDB

No variants for P21156

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P21156

No associated diseases with P21156

2 regional properties for P21156

Type Name Position InterPro Accession
binding_site Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site 35 - 53 IPR001216
domain Tryptophan synthase beta chain-like, PALP domain 9 - 294 IPR001926

Functions

Description
EC Number 2.7.7.4 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
sulfate adenylyltransferase complex (ATP) An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
sulfate adenylyltransferase (ATP) activity Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.

5 GO annotations of biological process

Name Definition
hydrogen sulfide biosynthetic process The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
sulfate assimilation The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
sulfate reduction The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.
sulfur compound metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDQIRLTHLR QLEAESIHII REVAAEFSNP VMLYSIGKDS SVMLHLARKA FYPGTLPFPL
70 80 90 100 110 120
LHVDTGWKFR EMYEFRDRTA KAYGCELLVH KNPEGVAMGI NPFVHGSAKH TDIMKTEGLK
130 140 150 160 170 180
QALNKYGFDA AFGGARRDEE KSRAKERIYS FRDRFHRWDP KNQRPELWHN YNGQINKGES
190 200 210 220 230 240
IRVFPLSNWT EQDIWQYIWL ENIDIVPLYL AAERPVLERD GMLMMIDDNR IDLQPGEVIK
250 260 270 280 290 300
KRMVRFRTLG CWPLTGAVES NAQTLPEIIE EMLVSTTSER QGRVIDRDQA GSMELKKRQG
YF