P20703

PR
Gene name
uvsW (dar)
Protein name
ATP-dependent DNA helicase uvsW
Names
CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, Dar protein
Species
Enterobacteria phage T4 (Bacteriophage T4)
KEGG Pathway
vg:1258733
EC number
3.6.4.12: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

524-587 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P20703

Entry ID Method Resolution Chain Position Source
1RIF X-ray 200 A A/B 1-282 PDB
2JPN NMR - A 512-587 PDB
2OCA X-ray 270 A A 1-502 PDB

No variants for P20703

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P20703

No associated diseases with P20703

4 regional properties for P20703

Type Name Position InterPro Accession
domain Helicase, C-terminal 337 - 443 IPR001650
domain Helicase/UvrB, N-terminal 127 - 260 IPR006935
domain Helicase superfamily 1/2, ATP-binding domain 110 - 300 IPR014001
domain UvsW.1 domain 532 - 585 IPR020975

Functions

Description
EC Number 3.6.4.12 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA helicase activity Unwinding of a DNA helix, driven by ATP hydrolysis.
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIKVHFHDF SHVRIDCEES TFHELRDFFS FEADGYRFNP RFRYGNWDGR IRLLDYNRLL
70 80 90 100 110 120
PFGLVGQIKK FCDNFGYKAW IDPQINEKEE LSRKDFDEWL SKLEIYSGNK RIEPHWYQKD
130 140 150 160 170 180
AVFEGLVNRR RILNLPTSAG KSLIQALLAR YYLENYEGKI LIIVPTTALT TQMADDFVDY
190 200 210 220 230 240
RLFSHAMIKK IGGGASKDDK YKNDAPVVVG TWQTVVKQPK EWFSQFGMMM NDECHLATGK
250 260 270 280 290 300
SISSIISGLN NCMFKFGLSG SLRDGKANIM QYVGMFGEIF KPVTTSKLME DGQVTELKIN
310 320 330 340 350 360
SIFLRYPDEF TTKLKGKTYQ EEIKIITGLS KRNKWIAKLA IKLAQKDENA FVMFKHVSHG
370 380 390 400 410 420
KAIFDLIKNE YDKVYYVSGE VDTETRNIMK TLAENGKGII IVASYGVFST GISVKNLHHV
430 440 450 460 470 480
VLAHGVKSKI IVLQTIGRVL RKHGSKTIAT VWDLIDSAGV KPKSANTKKK YVHLNYLLKH
490 500 510 520 530 540
GIDRIQRYAD EKFNYVMKTV NLISFGPLEK KMLLEFKQFL YEASIDEFMG KIASCQTLEG
550 560 570 580
LEELEAYYKK RVKETELKDT DDISVRDALA GKRAELEDSD DEVEESF