P20484

PR
Gene name
MAK11 (YKL021C)
Protein name
Protein MAK11
Names
Maintenance of killer protein 11
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YKL021C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-84 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P20484

Entry ID Method Resolution Chain Position Source
AF-P20484-F1 Predicted AlphaFoldDB

No variants for P20484

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P20484

No associated diseases with P20484

9 regional properties for P20484

Type Name Position InterPro Accession
repeat WD40 repeat 41 - 135 IPR001680-1
repeat WD40 repeat 138 - 186 IPR001680-2
repeat WD40 repeat 185 - 221 IPR001680-3
repeat WD40 repeat 289 - 339 IPR001680-4
conserved_site WD40 repeat, conserved site 164 - 178 IPR019775-1
conserved_site WD40 repeat, conserved site 317 - 331 IPR019775-2
repeat G-protein beta WD-40 repeat 122 - 136 IPR020472-1
repeat G-protein beta WD-40 repeat 164 - 178 IPR020472-2
repeat G-protein beta WD-40 repeat 317 - 331 IPR020472-3

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Nucleus membrane ; Peripheral membrane protein
  • Membrane associated
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

4 GO annotations of biological process

Name Definition
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAIGDKNQF RIIVGSYEHN ILCLSLDIPN QKENDAAKTP HFMPIFHFQA HSLSIKCLAV
70 80 90 100 110 120
SRRYLVSGSN DEHIRIYDLQ KRKELGTLLS HQGSITALQF SHPASSSEDA AVSKGSKNSK
130 140 150 160 170 180
WLLSASEDHK IMVWRVKDWE TVGTLKGHTA RVNDVDIHPT NRIAISVSDD HSIRLWNLMT
190 200 210 220 230 240
LRNAAVLKLR KYNTNGTCVR WLGAKGDYFA VGLRDRVLIY ETGSAKVFKE IVFQRKTLMH
250 260 270 280 290 300
IETHILPFDN KEYLSVGISD GNVHFYPCEE LFEKVEENEK QEDDDDKEDI SPAFSLLGHT
310 320 330 340 350 360
NRIKDFKFYT NEFGTYLVTI GSDGKIVVWD MSTKEQVAVY DCGERLNCLT LCDESIEKYN
370 380 390 400 410
TMKKRDAETA DIGDQSEVES DTEELKKIMF GEKKKLNKKK RKQLKKSKVS VELE