P20419

PR
Gene name
plc (cbp)
Protein name
Phospholipase C
Names
PLC, Cbp, Phosphatidylcholine cholinephosphohydrolase
Species
Paraclostridium bifermentans (Clostridium bifermentans)
KEGG Pathway
EC number
3.1.4.3: Phosphoric diester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

11-80 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P20419

Entry ID Method Resolution Chain Position Source
AF-P20419-F1 Predicted AlphaFoldDB

No variants for P20419

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P20419

No associated diseases with P20419

4 regional properties for P20419

Type Name Position InterPro Accession
domain Phox homology 208 - 379 IPR001683
domain Phospholipase D/Transphosphatidylase 641 - 668 IPR001736-1
domain Phospholipase D/Transphosphatidylase 941 - 968 IPR001736-2
domain Phospholipase D-like domain 815 - 984 IPR025202

Functions

Description
EC Number 3.1.4.3 Phosphoric diester hydrolases
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

3 GO annotations of molecular function

Name Definition
phosphatidylcholine phospholipase C activity Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine.
toxin activity Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
hemolysis in another organism The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKALKKVSNI LCVLGLCTLM GGTSYAWDGK KDGTGTHSLI AEHGLSMLNN DLSGNESQQV
70 80 90 100 110 120
KDNIKILNEY LGDLKLGSTY PDYDPNAYDL YQDHFYDPDT GNNFTIDNSW YASYPIYDTS
130 140 150 160 170 180
RNSVRKFATL AKNEWEKGNF KEATFLLGQG LHYLGDLNTP YHASNVTAVD SPGHVKYETF
190 200 210 220 230 240
VEERKDNYAL NTSGNDTTSG VYKEAMENPS FNKWMTQNSI KYAKIAKDLY YSHSTMSHSW
250 260 270 280 290 300
DDWDYSGREA IKNSQVCTAG FLYRFMNEVS NGNTGDNDSL TNEFNIVLKT ADNKYAGTDD
310 320 330 340 350 360
NVYFGFETNE GKKFEWKLDN AGNDFERNQV DNYILKTKDG EEVDINNISN YWIRKERLTS
370 380 390
ISDDWELSNF KLIANGKVIQ QQDVNKVFTG NETYYINK