P19919

PR
Gene name
coxL (OCA5_pHCG300310)
Protein name
Carbon monoxide dehydrogenase large chain
Names
CO dehydrogenase subunit L, CO-DH L
Species
Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) (Oligotropha carboxidovorans)
KEGG Pathway
ocg:OCA5_pHCG300310
EC number
1.2.5.3: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

7 structures for P19919

Entry ID Method Resolution Chain Position Source
1N5W X-ray 150 A B/E 1-809 PDB
1N60 X-ray 119 A B/E 1-809 PDB
1N61 X-ray 130 A B/E 1-809 PDB
1N62 X-ray 109 A B/E 1-809 PDB
1N63 X-ray 121 A B/E 1-809 PDB
1ZXI X-ray 170 A B/E 1-809 PDB
AF-P19919-F1 Predicted AlphaFoldDB

No variants for P19919

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P19919

No associated diseases with P19919

3 regional properties for P19919

Type Name Position InterPro Accession
domain Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead 35 - 144 IPR000674
domain Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain 177 - 422 IPR008274
domain Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain 450 - 740 IPR046867

Functions

Description
EC Number 1.2.5.3 With a quinone or similar compound as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

5 GO annotations of molecular function

Name Definition
carbon-monoxide dehydrogenase (acceptor) activity Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.
carbon-monoxide oxygenase activity Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.
copper ion binding Binding to a copper (Cu) ion.
iron ion binding Binding to an iron (Fe) ion.
molybdenum ion binding Binding to a molybdenum ion (Mo).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNIQTTVEPT SAERAEKLQG MGCKRKRVED IRFTQGKGNY VDDVKLPGML FGDFVRSSHA
70 80 90 100 110 120
HARIKSIDTS KAKALPGVFA VLTAADLKPL NLHYMPTLAG DVQAVLADEK VLFQNQEVAF
130 140 150 160 170 180
VVAKDRYVAA DAIELVEVDY EPLPVLVDPF KAMEPDAPLL REDIKDKMTG AHGARKHHNH
190 200 210 220 230 240
IFRWEIGDKE GTDATFAKAE VVSKDMFTYH RVHPSPLETC QCVASMDKIK GELTLWGTFQ
250 260 270 280 290 300
APHVIRTVVS LISGLPEHKI HVIAPDIGGG FGNKVGAYSG YVCAVVASIV LGVPVKWVED
310 320 330 340 350 360
RMENLSTTSF ARDYHMTTEL AATKDGKILA MRCHVLADHG AFDACADPSK WPAGFMNICT
370 380 390 400 410 420
GSYDMPVAHL AVDGVYTNKA SGGVAYRCSF RVTEAVYAIE RAIETLAQRL EMDSADLRIK
430 440 450 460 470 480
NFIQPEQFPY MAPLGWEYDS GNYPLAMKKA MDTVGYHQLR AEQKAKQEAF KRGETREIMG
490 500 510 520 530 540
IGISFFTEIV GAGPSKNCDI LGVSMFDSAE IRIHPTGSVI ARMGTKSQGQ GHETTYAQII
550 560 570 580 590 600
ATELGIPADD IMIEEGNTDT APYGLGTYGS RSTPTAGAAT AVAARKIKAK AQMIAAHMLE
610 620 630 640 650 660
VHEGDLEWDV DRFRVKGLPE KFKTMKELAW ASYNSPPPNL EPGLEAVNYY DPPNMTYPFG
670 680 690 700 710 720
AYFCIMDIDV DTGVAKTRRF YALDDCGTRI NPMIIEGQVH GGLTEAFAVA MGQEIRYDEQ
730 740 750 760 770 780
GNVLGASFMD FFLPTAVETP KWETDYTVTP SPHHPIGAKG VGESPHVGGV PCFSNAVNDA
790 800
YAFLNAGHIQ MPHDAWRLWK VGEQLGLHV