P19900

PR
Gene name
L3
Protein name
Hexon protein
Names
CP-H, Protein II
Species
Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12)
KEGG Pathway
vg:1460858
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

87-258 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P19900

Entry ID Method Resolution Chain Position Source

No variants for P19900

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P19900

No associated diseases with P19900

2 regional properties for P19900

Type Name Position InterPro Accession
domain Adenovirus Pll, hexon, N-terminal 8 - 602 IPR016107
domain Adenovirus Pll, hexon, C-terminal 603 - 825 IPR016108

Functions

Description
EC Number
Subcellular Localization
  • Virion
  • Host nucleus
  • Forms the capsid icosahedric shell
  • Present in 720 copies per virion, assembled in 240 trimers
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
T=25 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.

1 GO annotations of molecular function

Name Definition
structural molecule activity The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.

2 GO annotations of biological process

Name Definition
microtubule-dependent intracellular transport of viral material towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.
viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATPSMMPQW SYMHIAGQDA SEYLSPGLVQ FARATDTYFT LGNKFRNPTV APTHDVTTDR
70 80 90 100 110 120
SQRLTLRFVP VDREDTTYSY KARFTLAVGD NRVLDMASSY FDIRGVLDRG PSFKPYSGTA
130 140 150 160 170 180
YNSLAPKGAP NASQWSDNAK LNTFAQAPYL SDTITAADGI KVGTDTAQAG AAVYANKTYQ
190 200 210 220 230 240
PEPQVGPSEW NTSIENVKAG GRALKQTTAM QPCYGSYARP TNEHGGQSKD DNIELKFFDS
250 260 270 280 290 300
ANNAANTAQV VFYTEDVNLE MPDTHLVFKP TVTNGTIASE SLLGQQAAPN RANYIAFRDN
310 320 330 340 350 360
FIGLMYYNST GNMGVLAGQA SQLNAVVDLQ DRNTELSYQL MLDALGDRTR YFSLWNSAVD
370 380 390 400 410 420
SYDPDVRVIE NHGVEDELPN YCFPLSAVGE IKNYKGIKPD NGGGGGWTAD NTVSEANHIG
430 440 450 460 470 480
IGNIAAMEIN LQANLWRSFL YSNVGLYLPD DLKYTPGNIK LPDNKNTYEY MNGRVTAPGL
490 500 510 520 530 540
VDTYVNIGAR WSPDVMDNVN PFNHHRNAGL RYRSMLLGNG RFVPFHIQVP QKFFAIRNLL
550 560 570 580 590 600
LLPGSYTYEW NFRKDVNMIL QSTLGNDLRV DGASVRFDNI ALYANFFPMA HNTASTLEAM
610 620 630 640 650 660
LRNDTNDQSF NDYLCAANML YPIPANATSV PISIPSRNWA AFRGWSFTRL KTKETPSLGS
670 680 690 700 710 720
GFDPYFVYSG TIPYLDGTFY LNHTFKKVSI MFDSSVSWPG NDRLLTPNEF EIKRSVDGEG
730 740 750 760 770 780
YNVAQCNMTK DWFLIQMLSH YNIGYQGFYI PESYKDRMYS FFRNFQPMSR QVVDTTEYKN
790 800 810 820 830 840
YKKVTVEFQH NNSGFVGYLG PTMREGQAYP ANYPYPLIGQ TAVESITQKK FLCDRVMWRI
850 860 870 880 890 900
PFSSNFMSMG ALTDLGQNML YANSAHALDM TFEVDPMDEP TLLYVLFEVF DVVRIHQPHR
910
GVIEAVYLRT PFSAGNATT