P19587

PR
Gene name
rpoA
Protein name
DNA-directed RNA polymerase subunit alpha
Names
PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha
Species
Tetradesmus obliquus (Green alga) (Acutodesmus obliquus)
KEGG Pathway
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

160-298 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P19587

Entry ID Method Resolution Chain Position Source
AF-P19587-F1 Predicted AlphaFoldDB

1 variants for P19587

Variant ID(s) Position Change Description Diseaes Association Provenance
3 K>E strain: KS3/2 [UniProt] No

No associated diseases with P19587

2 regional properties for P19587

Type Name Position InterPro Accession
domain DNA-directed RNA polymerase, insert domain 61 - 148 IPR011262
domain DNA-directed RNA polymerase, RpoA/D/Rpb3-type 24 - 338 IPR011263

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
protein dimerization activity The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKKIQDFFL SCKECILENP RSFYGSFSLG PFKNSQSLTV ANALRRTLLA ELSNIAITHL
70 80 90 100 110 120
EIEGVTHEYS TLVGVRESVL DLLLNFKGIA LKNTSPVTKP LFGYLQVRGP GVVRASDLKF
130 140 150 160 170 180
PPMIQCVDPD QYIATLNENG KLILKFRISD FKNSQENLNF EVSKTFLNIP NFGHFDTSSF
190 200 210 220 230 240
QNFENSNFFS SSFFASQKMI KSKRKTKFSQ LKVDYLSSFG FSTQHKRSGL NQTQKFAMQH
250 260 270 280 290 300
QNPFRIEKNQ QDFNKNKNGN FDSQKNKTNS LWVDPLFNPI LKVNYIIETI EPMQKNIPNE
310 320 330 340 350 360
IVFIELWTNG SIHPRKAFYT ALLYLKTMFD KLDCMRLLNY EFSNTMLESE KTSTKFFKTF
370 380 390 400 410 420
EYDFRFYNSR EDKTMKSFTP EKFFLPEEIE DVEKDYLLNL KNQADNTWND LPLTNLNLPY
430 440 450 460 470
RITKILAKNN FFVVGDLLKI SPNELKKLSG IGNYCVFILQ KRFEKLGLKL GSRNEKNL